{"product_id":"lipid-support-complex","title":"Lipid Support Complex","description":"\u003ch5\u003ePure Encapsulations Lipid Support Complex\u003c\/h5\u003e\n\u003cp\u003e\u003cem\u003eLiver \u0026amp; Detoxification \u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eLipid Support Complex supports hepatic fat metabolism with a combination of berberine and clinically studied Bergacyn®FF, a patented extract blend of bergamot citrus and Cynara cardunculus. Bergacyn®FF supports lipid metabolism in the liver, with the added benefits of supporting healthy uric acid levels, decreasing oxidative stress and supporting vascular endothelial health.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis formula also provides berberine, an alkaloid that moderates lipid accumulation in liver cells in vitro.\u003c\/span\u003e\u003cspan\u003e In preclinical models, berberine activates hepatic AMP kinase (AMPK) and sirutin 1 (SIRT1), which play important roles in supporting fat utilization in moderating fat synthesis in the liver.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey Benefits \u0026amp; Features: \u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eSupports hepatic fat metabolism\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eReduces oxidative stress\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSupports vascular health\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePromotes healthy uric acid levels\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eClinically studied BergacynFF\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eIngredients\u003c\/span\u003e\u003c\/h3\u003e\n\u003ctable style=\"width: 100%; height: 101.625px;\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 97.1119%; height: 19.5938px;\"\u003e\u003cstrong\u003eServing Size: 2 Vegetarian Capsules\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 2.52708%; height: 19.5938px;\"\u003e\u003cstrong\u003eAmount\/Serving\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 23.25px;\"\u003e\n\u003ctd style=\"width: 97.1119%; height: 23.25px;\"\u003e\u003cstrong\u003eBergaCynFF\u003csup\u003e®\u003c\/sup\u003e blend\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 2.52708%; height: 23.25px;\"\u003e600 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 97.1119%; height: 39.1875px; padding-left: 40px;\"\u003eBergamot orange (Citrus bergamia) extract (fruit) and Artichoke (Cynara cardunculus) extract (leaf) (standardized to 17% flavonoids)\u003c\/td\u003e\n\u003ctd style=\"width: 2.52708%; height: 39.1875px;\"\u003e\u003cbr\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 97.1119%; height: 19.5938px;\"\u003eBerberine HCI\u003c\/td\u003e\n\u003ctd style=\"width: 2.52708%; height: 19.5938px;\"\u003e500 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003eOther Ingredients:\u003c\/strong\u003e Vegetarian capsule (cellulose, water), hypoallergenic plant fiber (cellulose), ascorbyl palmitate, tri-magnesium citrate. \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes Not Contain: \u003c\/strong\u003eWheat, soy, dairy, eggs, artificial colors or sweeteners, coatings, shellacs, GMOs, tree nuts, peanuts, sesame, unnecessary binders, fillers or preservatives, magnesium stearate, gluten, trans fat, or hydrogenated oils. \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eGluten-Free, Dairy-Free, Soy-Free, Non-GMO \u003c\/em\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eSuggested Use\u003c\/span\u003e\u003c\/h3\u003e\n\u003cdiv class=\"accordion-item\"\u003e\n\u003cdiv aria-hidden=\"false\" aria-labelledby=\"accordion-header-0\" role=\"region\" id=\"accordion-panel-0\" class=\"accordion-panel open\"\u003e\n\u003cdiv class=\"accordion-attribute-container\"\u003e\n\u003cdiv class=\"accordion-attribute accordion-attribute-suggested_use\"\u003e\n\u003cp\u003eAs a dietary supplement, take 2 capsules daily with meals, or as directed by a health care professional.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarning: \u003c\/strong\u003eNot to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Store in a cool, dry place.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"accordion-item\"\u003e\n\u003cdiv aria-controls=\"accordion-panel-1\" id=\"accordion-header-1\" aria-expanded=\"false\" role=\"button\" class=\"accordion-header\" tabindex=\"0\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch3\u003e\u003cspan\u003eMore Info. \u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eLipid Support Complex supports hepatic fat metabolism with a combination of berberine and clinically studied BergacynFF\u003csup\u003e®\u003c\/sup\u003e, a patented extract blend of bergamot citrus and \u003cem\u003eCynara cardunculus\u003c\/em\u003e. BergacynFF\u003csup\u003e®\u003c\/sup\u003e supports lipid metabolism in the liver, with the added benefits of promoting healthy uric acid levels, decreasing oxidative stress, and supporting vascular endothelial health. In a randomized, double blind, placebo-controlled clinical study involving 102 subjects, BergacynFF\u003csup\u003e®\u003c\/sup\u003e (600 mg\/day) for 12 weeks resulted in significant support for liver fat metabolism, assessed by CAP scores. In a randomized, double blind, placebo-controlled clinical study involving 80 subjects, BergacynFF\u003csup\u003e®\u003c\/sup\u003e (600 mg\/day) significantly improved serum markers of oxidative stress, with a reduction in circulating malondialdehyde (MDA) coupled with an increase in glutathione peroxidase (GPx) and superoxide dismutase (SOD) levels after 16 weeks. Supplementation also supported vascular endothelial function. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIndications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAges 18 and up\u003c\/li\u003e\n\u003cli\u003ePatients seeking support for healthy liver fat metabolism\u003c\/li\u003e\n\u003cli\u003ePatients seeking support for healthy uric acid levels or oxidative stress\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSource\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBergamot orange extract is derived from\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eCitrus bergamia\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003efruit\u003c\/li\u003e\n\u003cli\u003eCardoon artichoke extract is derived from\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eCynara cardunculus\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eleaf\u003c\/li\u003e\n\u003cli\u003eAscorbyl palmitate is derived from corn dextrose fermentation and palm oil\u003c\/li\u003e\n\u003cli\u003eHypoallergenic plant fiber is derived from pine cellulose\u003c\/li\u003e\n\u003cli\u003eTri-magnesium citrate is derived from elemental ore and non-GMO glucose fermentation from non-GMO maize, molasses, and sugar beet or sugar cane\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWho Is This Supplement For?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePatients seeking support for healthy liver fat metabolism\u003c\/li\u003e\n\u003cli\u003ePatients seeking support for healthy uric acid levels\u003c\/li\u003e\n\u003cli\u003ePatients aiming to reduce oxidative stress\u003c\/li\u003e\n\u003cli\u003ePatients who wish to maintain liver health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMechanisms of Action \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAMPK activation.\u003c\/strong\u003e Berberine is an alkaloid that moderates lipid accumulation in liver cells in vitro. In preclinical models, berberine activates hepatic AMP kinase (AMPK) and sirtuin 1 (SIRT1), which play important roles in supporting fat utilization in moderating fat synthesis in the liver.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHepatic lipid metabolism\u003c\/strong\u003e. The polyphenolic fraction of bergamot promotes the hepatic catabolism of fatty acids by supporting beta-oxidation, a mitochondrial pathway where fatty acids are broken down to produce energy. Preclinical data suggest that it also supports lysosomal degradation of intracellular lipids.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAntioxidant effects.\u003c\/strong\u003e  Clinically significant antioxidant efficacy was demonstrated in subjects receiving Bergacyn®FF, with a 24% mean reduction in circulating malondialdehyde (MDA), a biomarker of oxidative stress, in a 16-week clinical trial. Bergamot polyphenols support Nrf2 signaling, which promotes expression of antioxidant genes such as glutathione peroxidase and superoxide dismutase.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEndothelial function\u003c\/strong\u003e. Significant support for vascular reactivity (assessed via EndoPAT methodology) occurred subjects supplemented with Bergacyn® FF in a 16 week study, suggesting that the extracts may influence nitric oxide release from endothelial cells.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eClinical Research Highlights \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn a randomized, double blind, placebo-controlled clinical study involving 86 subjects (mean age 51 ± 9 years) Bergacyn®FF (600 mg\/day) for 12 weeks resulted in significant support for liver fat metabolism, assessed by CAP scores. The study found that Bergacyn®FF effectively moderated liver ultrasound-based CAP scores in individuals over 50 years of age with a mean decrease of −48.2 ± 39 dB\/m compared to −26.9 ± 43 dB\/m in the placebo group. After adjusting for weight change, participants over 50 exhibited a 78% reduction after supplementation versus 44% in the placebo group.\u003c\/p\u003e\n\u003cp\u003eIn a randomized, double blind, placebo-controlled clinical study involving 80 subjects (mean age 51 ± 10 years), Bergacyn®FF (600 mg\/day) significantly improved serum markers of oxidative stress, with a 24% reduction in circulating malondialdehyde (MDA), a 13.8% increase in glutathione peroxidase (GPx) and a 29% increase superoxide dismutase (SOD) levels after 16 weeks. Supplementation also supported markers of liver function (gamma-glutamyltransferase and alkaline phosphatase). Additionally, favorable changes in vascular endothelial function were detected via reactive hyperemia Index, Framingham’s Hyperemia Index and Augmentation Index scores, assessed via the EndoPAT procedure.\u003c\/p\u003e\n\u003cp\u003eIn a 6-week randomized, double blind, placebo-controlled clinical study involving 94 subjects (age 30-70), subjects receiving Bergacyn FF (600mg\/day) significantlly promoted healthier serum uric acid levels  (-0.1+ 0.7 mg\/dL), in contrast to an elevation of 0.3 ± 0.7 mg\/dL observed with placebo.1  Serum uric acid levels remained unchanged in participants with the lowest baseline measurements, while subjects with higher baseline levels (\u0026gt;5.4 mg\/dL) experienced a significant change (−7.8%) compared to those in the lowest baseline levels (+4.9%).\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"60 Capsules","offer_id":42103151132759,"sku":"ATR-LSC6","price":60.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0193\/9503\/files\/Lipid_Support_Complex_Front-removebg-preview.png?v=1762812061","url":"https:\/\/www.healthyhabitsliving.com\/products\/lipid-support-complex","provider":"Healthy Habits Living","version":"1.0","type":"link"}