Douglas Laboratories Methyl Folate 5 mg
Methyl Folate supplies 5 mg of biologically active folate called (6S) 5-methyltetrahydrofolate (5-MTHF). 5-MTHF is the naturally occurring, predominant form of folate commonly found in cells and is essential for overall health, as it participates as a cofactor in a reaction that involves the remethylation of homocysteine to methionine. Quatrefolic® is a highly soluble glucosamine salt of 5-MTHF that has demonstrated more rapid absorption than folic acid.
Each serving contains:
Folate - 5 mg
(as Quatrefolic® (6S)-5-Methyltetrahydrofolic acid, glucosamine salt)
Other ingredients: Microcrystalline cellulose and hydroxypropyl methylcellulose (capsule).
As a dietary supplement, adults take 1 capsule daily or as directed by a healthcare professional.
Folate is a vitamin that humans cannot synthesize or store well because of its water soluble nature. Folates are normally found in a wide variety of foods and are commonly consumed through a diet of green leafy vegetables, sprouts, fruits, and animal products such as milk and dairy products, egg yolk and liver, however, storage and heat during cooking may decrease the bioavailability by almost 95%. Folic acid and food containing folate are not biologically active in the human body. To convert these forms to the biologically active 5-methyltetrahydrofolate (5-MTHF) requires a key enzyme, methylenetetrahydrofolate reductase (MTHFR), which is considered one of the most important enzymes in human physiology. There is a large percentage of the population with a genetic mutation that limits the conversion of folate to its reduced active form, MTHF.