{"product_id":"pms-nutritional-support-120-capsules","title":"PMS Nutritional Support","description":"\u003ch5\u003eNutriCology PMS Nutritional Support\u003c\/h5\u003e\n\u003cp\u003eDIM (diindolylmethane) has been shown to help regulate and promote a more efficient metabolism of estrogen, and an optimal ratio of estrogen metabolites. \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePMS Nutritional Support\u003c\/strong\u003e contains BioResponse DIM®, a unique formulation containing pure diindolylmethane, an indole. Indoles are plant compounds with health promoting properties, and are found in cruciferous vegetables such as broccoli, cabbage, cauliflower and Brussels sprouts. The phytochemicals in cruciferous vegetables have been shown to beneficially affect the body’s hormonal and detoxification systems, and epidemiological studies support the health benefits of consuming these vegetables. DIM is a major active acid-catalyzed derivative of one of the phytochemicals in cruciferous vegetables, indole-3-carbinol (I3C). DIM is thought to be responsible for the health effects of dietary I3C. PMS Nutritional Support contains a stable, bioavailable form of DIM, made possible through a proprietary delivery system. The formula is co-solubilized with phosphatidylcholine, and microencapsulated in starch particles.\u003c\/p\u003e\n\u003cp\u003ePMS Nutritional Support is completed with the addition of Vitex standardized extract, bioactive vitamin B6 as pyridoxal-5-phosphate, chromium picolinate, and magnesium aspartate.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey Features:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePromotes healthy reproductive hormonal metabolism and balance\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eHelps promote the conversion of estrogen to its beneficial, protective \u003cbr\u003e2-hydroxyestrone metabolites and reduces production of genotoxic 16α-hydroxyestrone\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eStimulates detoxification enzyme systems\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ctable style=\"width: 100%; height: 176.344px;\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 65.9926%; height: 19.5938px;\"\u003e\u003cstrong\u003eServing Size: 2 Vegetarian Capsules\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 33.6397%; height: 19.5938px;\"\u003e\u003cstrong\u003eAmount\/Serving\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 65.9926%; height: 19.5938px;\"\u003e\n\u003cdiv class=\"ing-2-l\"\u003eVitamin B6 (as Pyridoxal-5-Phosphate)\u003c\/div\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 33.6397%; height: 19.5938px;\"\u003e\n\u003cdiv class=\"ing-2-r\"\u003e25 mg\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 65.9926%; height: 19.5938px;\"\u003e\n\u003cdiv class=\"ing-2-l\"\u003eMagnesium (as Magnesium Aspartate)\u003c\/div\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 33.6397%; height: 19.5938px;\"\u003e\n\u003cdiv class=\"ing-2-r\"\u003e50 mg\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.5938px;\"\u003e\n\u003ctd style=\"width: 65.9926%; height: 19.5938px;\"\u003e\n\u003cdiv class=\"ing-2-l\"\u003eChromium (as Chromium Picolinate)\u003c\/div\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 33.6397%; height: 19.5938px;\"\u003e\n\u003cdiv class=\"ing-2-r\"\u003e50 µg\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 58.7812px;\"\u003e\n\u003ctd style=\"width: 65.9926%; height: 58.7812px;\"\u003e\n\u003cdiv class=\"ing-2-l\"\u003eBioResponse DIM® (A proprietary Diindolylmethane complex-starch, DIM (25% min.), vitamin E (as tocophersolan), phosphatidylcholine (sunflower), silica)\u003c\/div\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 33.6397%; height: 58.7812px;\"\u003e\n\u003cdiv class=\"ing-2-r\"\u003e150 mg\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.1875px;\"\u003e\n\u003ctd style=\"width: 65.9926%; height: 39.1875px;\"\u003e\n\u003cdiv class=\"ing-2-l\"\u003e\n\u003cdiv class=\"ing-2-l\"\u003e\n\u003cem\u003eVitex agnus-castus\u003c\/em\u003e (Berry) Extract (Standarized to 0.5% Agnusides)\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 33.6397%; height: 39.1875px;\"\u003e\n\u003cdiv class=\"ing-2-r\"\u003e\n\u003cdiv class=\"ing-2-r\"\u003e75 mg\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003eOther Ingredients: \u003c\/strong\u003eGelatin, glycerin, purified water, yellow beeswax, carob extract, zinc oxide.\u003c\/p\u003e\n\u003ch3\u003eSuggested Use\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eAs a dietary supplement, 2 capsules one or two times daily with meals, or as directed by a healthcare practitioner.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarning: \u003c\/strong\u003eDo not use this product if you are pregnant or lactating, or using birth control pills. Persons taking prescription medications should consult a healthcare professional before use. Harmless changes in urine color may occur. Keep out of reach of children.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e \u003cspan\u003eKeep in a cool, dry place, tightly capped. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eMore Info\u003c\/h3\u003e\n\u003cp\u003eResearch over the past thirty years has determined that healthy estrogen metabolism is closely linked to several healthy parameters in men and women, particularly some involving the breast, uterus, prostate and other reproductive tissue. Genetics, excess weight, poor diet and other lifestyle factors may result in an imbalance of estrogen metabolites. Xenoestrogenic compounds, such as organochlorine pesticides, can also significantly disrupt healthy estrogen metabolism.\u003c\/p\u003e\n\u003cp\u003eThese estrogen disruptors alter estradiol hydroxylation metabolism producing a higher ratio of the genotoxic 16α-hydroxyestrone (16α-OHE1) to the safer and weaker estrogenic 2-hydroxyestrone (2-OHE1). The genotoxic 16α-OHE1 can potentially disrupt several normal cellular metabolic processes. DIM promotes the conversion of estrogen to its beneficial, protective 2-hydroxyestrone metabolites and reduces production of genotoxic 16α-OHE1. Modulating these aspects of estrogen metabolism, particularly the production of 16α-OHE1, may contribute to healthy aging.\u003c\/p\u003e\n\u003cp\u003eThe mechanisms for DIM’s health benefits primarily involve the induction of mixed function oxidases and phase II detoxification enzyme systems by the binding and activation of the arylhydrocarbon receptor (AhR). Research using human breast cells (MCF-7) has shown that the binding of DIM to the aryl hydrocarbon receptor can result in rapid formation of the nuclear AhR complex and consequent induction of gene expression and synthesis of cytochrome P450 detoxification enzyme (CyP450A1). DIM consequently produces increased levels of the protective hydroxylated estrogen 2-OHE1. Some have suggested that DIM may also positively affect cellular signaling pathways. It is becoming increasingly apparent that DIM may provide an important mechanism for supporting successful aging despite the increasing levels of xenoestrogenic compounds in our modern world.\u003c\/p\u003e\n\u003cp\u003eThe berries of the \u003cstrong\u003echaste tree\u003c\/strong\u003e (Vitex agnus–castus) have been used for millennia to support women’s health. Modern clinical studies confirm the potential for chasteberry to significantly support the health of women’s reproductive system and healthy moods. \u003cstrong\u003eVitamin B6\u003c\/strong\u003e in the bioactive form of pyridoxal-5-phosphate (P5P) helps promote production of the calming neurotransmitters serotonin and gamma-aminobutyric acid (GABA). It combines especially well with \u003cstrong\u003emagnesium,\u003c\/strong\u003e which also supports vasodilation, helps relax muscles, and supports healthy moods. \u003cstrong\u003eChromium\u003c\/strong\u003e supports healthy blood sugar levels and insulin sensitivity.\u003c\/p\u003e","brand":"Nutricology","offers":[{"title":"120 capsules","offer_id":41817070272599,"sku":"NTC-54720","price":61.19,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0193\/9503\/files\/54720__11474-Photoroom.png?v=1744927434","url":"https:\/\/www.healthyhabitsliving.com\/products\/pms-nutritional-support-120-capsules","provider":"Healthy Habits Living","version":"1.0","type":"link"}