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Activated B vitamins + TMG
This Methyl Balance™ supplement features Trimethylglycine (also known as betaine) and active forms of vitamins B12, B6, B2, and folate. Together, these ingredients offer support for heart health, brain function, and mood.
These key nutrients help maintain healthy levels of homocysteine in your blood, which is essential for keeping your heart in good shape.
Methylation, which is vital for cellular health, hormone and neurotransmitter production, and energy metabolism, relies heavily on these optimal levels of B vitamins, which are also linked to enhanced neurological and psychological health.
This Methyl Balance™ formula provides optimal levels of B vitamins in their most bioavailable forms, which is necessary for your neurological and mental health.
It features Metafolin®, a specialized form of folate readily utilized by the body, eliminating the need for complex breakdown processes. This makes Methyl Balance™ highly effective for various genetic backgrounds, enhancing support for essential body functions.
Benefits
Key Features
|
Serving Size: 1 Vegetarian Capsule |
Amount/Serving |
| Riboflavin (as riboflavin 5’-phosphate) | 30 mg |
| Vitamin B6 (as pyridoxal 5’- phosphate) | 15 mg |
| Folate (as Metafolin®‡ calcium L-5- methyltetrahydrofolate) | 1,360 mcg DFE (800 mcg) |
| Vitamin B12 (as methylcobalamin) | 1,000 mcg |
| Betaine (trimethylglycine) | 600 mg |
Other Ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), ascorbyl palmitate, microcrystalline cellulose, and silicon dioxide.
Made without common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat/gluten, soybeans, and sesame. Non-GMO. Vegan. No synthetic colors or flavors.
‡Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany.
Adults: 1 capsule daily with food as needed or as directed by a healthcare professional.
Children: As directed by a healthcare professional.
Caution: Methyl Balance™ should not replace any medication. Consult a physician if you are pregnant or nursing, have a medical condition, are taking prescription drugs, or are under 18 years old. KEEP OUT OF REACH OF CHILDREN.
Storage: Do not use if shrinkwrap is broken or missing. Store at room temperature (59°F-85°F).
Methylation is a biochemical reaction involving the transfer of a one-carbon methyl group from one molecule to another. This deceptively simple molecular modification is critically important and enables living organisms to alter protein functions and cellular activities in response to changes in both internal and external environmental conditions. For example, in neural tissue, methylation of phospholipids helps regulate cell membrane fluidity and mediate cognition and neuronal synchronization. In pancreatic islet cells, methylation supports glucose-stimulated insulin secretion. Methylation of DNA is an important means of regulating gene expression and nuclear chromatin organization.
Methylation activity is directly influenced by key nutrients such as B vitamins, betaine, and SAMe. One approach to optimizing methylation capacity in the body is to increase intake of nutritional cofactors that support production of SAMe and reduce the buildup of metabolites that may obstruct cellular methylation pathways. The most important nutrients to support healthy methylation are the active, coenzyme forms of vitamins B2, B6, B12, folate, and betaine.
Metabolizing homocysteine is also an important step in maintaining healthy cardiovascular and cognitive function. Vitamin B6, B12, and folate work together to metabolize homocysteine to methionine. Betaine further supports the metabolism of homocysteine to methionine through an alternate pathway.





