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WynnPharm DONA - Product Review

by Carly Neubert, BA, NC on April 27, 2020

WynnPharm, also known as Wynn Pharmacy, is a company originally created in 2005 to take over the distribution from Rotta Pharmaceuticals, Inc. They now offer a variety of unique brands and products for various issues, including joint health, women’s health, pain relief, and vitamins and minerals. Their most unique formula is DONA, a joint health and flexibility supplement that uses crystalline glucosamine sulfate. It is used to maintain and stabilize the cartilage between your joints. Whatever your age group, you need to be paying attention to your joint health so that you remain mobile and pain-free. 

What is WynnPharm DONA?

DONA is a glucosamine supplement used for joint health. It isn’t a standard discount brand glucosamine. Every supplement store and pharmacy carries glucosamine supplements. You can even find bargain sized bottles at Costco, Walmart, and Amazon. But DONA utilizes a unique patented crystalline glucosamine sulfate format. You won’t find DONA’s patented crystalline glucosamine sulfate in bargain brand glucosamine products.

Glucosamine is naturally occurring in your body and more specifically in your cartilage. Your joints are the points in your body where two bones meet and are held together by fibrous tissue called cartilage. An example is your knee joint. This is where your femur and tibia meet. Your body uses glucosamine to make the cartilage that surrounds and holds together your femur and tibia.

If you body doesn’t make enough cartilage, you run the risk of joint problems and pains.

Glucosamine is not only useful for managing your cartilage and joint health, it is also used to treat interstitial cystitis and inflammatory bowel disease. Glucosamine has been shown to help treat various conditions and disorders, including osteoarthritis and Rheumatoid arthritis. It reduces inflammation and strengthens cartilage and synovial fluid.

In some studies, glucosamine has been shown to protect joint tissues and prevent the breakdown of the joint. This reduces the chance of needing knee and other joint replacements in the future. In fact, one of the studies on glucosamine sulfate indicated that by taking it, you can reduce your chances of total knee replacement by up to 73%.

Glucosamine supplements are commonly recognized to aid with:

  • osteoarthritis (OA)
  • glaucoma
  • weight loss
  • interstitial cystitis, a bladder condition
  • jaw pain
  • joint pain, such as knee pain
  • back pain
  • multiple sclerosis (MS)
  • inflammatory bowel disease (IBD) and ulcerative colitis.

WynnPharm DONA Ingredients & Interactions

Like most glucosamine supplements, DONA is derived from shellfish. Avoid DONA glucosamine supplements if you have a shellfish allergy. Glucosamine may also affect your blood sugar levels, so stop taking glucosamine two weeks before elective surgery to ensure your blood sugar levels stay steady during and after surgery.

There aren’t many drug interactions with glucosamine, but there are a couple. Namely, glucosamine can interact with both acetaminophen (Tylenol for example) and Warfarin (Coumadin, Jantoven). The interaction between acetaminophen and glucosamine can lead to reduced effectiveness of both glucosamine and acetaminophen.

On the other hand, the interaction with Warfarin can lead to increased effects of Warfarin as an anticoagulant, increasing your risk of bleeding and reducing the chance that your blood will clot properly if you become injured. Check with your doctor if you are taking a blood thinner.

DONA Reviews & Testimonials

There are hundreds of online reviews for WynnPharm's DONA. From our site, one of our top reviews states “Dona helps relieve pain!” details James C.’s experience with DONA: “I suffer from severe pain over areas of my body. I find Dona helps take away some of my aches and pains!! Thank you.” Cathy, from WynnPharm’s site reviews, says “Keeps me from crying when I walk upstairs….I’ve tried a few others and they were worthless. If it wasn’t for Dona I wouldn’t have been able to move in with my husband because of the stairs.”

Overall, DONA has many glowing reviews, most of which are raving over the effectiveness of DONA and how it has positively affected their lives.

Why is crystalline better than sulfate or hydrochloride?

There is a common misconception that all glucosamine supplements are the same, regardless of their structure, but this simply is not true. Crystalline glucosamine sulfate is more absorbable than hydrochloride due to the different chemical structures. There have been over 150 pre-clinical and clinical studies showing the effectiveness of crystalline glucosamine sulfate and pointing out the reduced benefits of glucosamine hydrochloride.

The devil is in the details for this supplement. The medical research clearly shows the crystalline form is better absorbed and more effective. DONA is the only glucosamine supplement with the crystalline sulfate.


Glucosamine supplements are a dime a dozen. But if you want glucosamine that has been studied and proven to rebuild cartilage, then DONA should be your choice. No other glucosamine supplement currently uses the crystalline structure, which allows for more absorption and better effectiveness. I recommend DONA, by WynnPharm. With its crystalline glucosamine sulfate structure, you get the best quality and most effectiveness of any glucosamine supplement on the market today.


Carly Neubert BA, NC

For additional recipes, biohacking tips and lifestyle hacks -- check out my other blog on my coaching site www.cleancoachcarly.com! I post weekly about nutrition and lifestyle topics, all backed by science. Happy Reading!

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