Douglas Laboratories Bilex
Bilex is a dietary enzyme formula with pancreatin and papain for protein, carbohydrate and fat digestion, along with the addition of ox bile extract to help break down and assimilate lipids in the intestinal tract.
Each serving contains:
Pancreatin (8X) (from porcine) - 47 mg
Amylase - 9,400 USP units
Protease - 9,400 USP units
Lipase - 752 USP units
Papain (from papaya) - 372,000 USP units
Ox Bile Powder - 380 mg
Other ingredients: Cellulose, vegetable stearate and silica.
As a dietary supplement, adults take 3 tablets daily with meals or as directed by your healthcare professional.
The pancreas supplies the major digestive enzymes that catalyze the breakdown of starches (carbohydrates), proteins, and fats, so that the breakdown products can be absorbed in the upper small intestine. Some carbohydrate digestion takes place in the mouth by salivary amylase, but pancreatic amylase is the major carbohydrate-digesting enzyme. Amylases break down starches to maltose and maltotriose, which are further hydrolyzed into glucose by the disaccharidases of the mucosal cells, and then absorbed. Although cellulose is indigestible by pancreatic and intestinal enzymes, the microflora within the large intestine may degrade it and produce uncomfortable symptoms in the process. Although fat digestion starts in the mouth with the action of salivary lipase, the great majority of fat triglycerides are digested by pancreatic lipase secreted by the exocrine pancreas into the duodenum.
Lipases break down triglycerides into monoglycerides and free fatty acids, which are efficiently absorbed in the upper small intestine. Protein digestion is initiated in the stomach by pepsin and hydrochloric acid, which denature and break large proteins down to smaller polypeptides. In the small intestine, proteases break down these polypeptides into free amino acids, and di- and tripeptides, which are directly absorbed by the intestinal mucosa. Papain is a protease enzyme derived from papaya and is an enzyme that breaks peptide bonds. Bile is normally secreted by the gallbladder to digest fat. Ox bile is very similar to human bile to help aid in digestion and assimilation of lipids in the small intestine.