Calm CP - 60 Capsules

Description

NeuroScience Calm CP

Decrease cortisol to maintain healthy activity while providing ingredients important for optimal sleep, calm, and management of healthy blood sugar

Patient Profile:

• Experiencing stress (acute, sustained or immune)
• Consistently interrupted sleep
• Difficulty falling back asleep
• New or increasing abdominal fat

The Science:

• In response to stress, the sympathetic nervous system (SNS) and hypothalamic-pituitary-adrenal (HPA) axis signal to the adrenals to release catecholamines (norepinephrine and epinephrine) and cortisol
• While stress is a normal part of life, it can also be associated with imbalances in the HPA axis that can affect catecholamine and cortisol activity 

Ingredients

Other Ingredients: Organic rice concentrate, vegetable capsule (hypromellose, water), and silica. 

Suggested Use

Take 2 capsules one to two times daily or as directed by your healthcare provider. Do not exceed the suggested use.

Warning: If you are pregnant or nursing, consult your healthcare provider before use. Keep out of reach of children.

Storage: This product has a tamper-evident seal under the cap. Do not use if the seal is broken or missing. Store at room temperature, in a dry place. 

More Info.

Stress, cortisol, and weight

Cortisol secretion follows a marked circadian pattern and increases in response to stress through activation of the HPA axis

• Adipocytes (fat cells) play a major role in the body’s production of cortisol

High stress has been linked to less healthy dietary behaviors and increased body weight

• Cortisol inhibits the secretion and actions of insulin (glucose uptake, central appetite reduction)
• Cortisol promotes the maturation of adipocytes (fat cells)
• Upregulation of the enzyme 11β-HSD1 promotes fat accumulation by increasing cortisol levels
• Elevated bedtime cortisol levels are associated with increased abdominal fat

Proven benefits of Calm CP

A randomized study with corosolic acid was shown to significantly lower blood glucose levels

• 10 subjects were prescreened and selected to receive corosolic acid once daily for 15 days
• Blood glucose levels were 20-30% lower after two weeks

The effectiveness of Calm CP was analyzed in a study

• Participants were prescreened for elevated cortisol levels
• Calm CP (2 capsules twice daily for 4 days) significantly lowered total daily cortisol levels (area under the curve - AUC) compared to baseline values 
• Calm CP decreased mean daily cortisol levels by 17%
• 71% of participants reported they would take Calm CP again