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Bladder Support
Cysto Renew®, developed by Dr. Geo Espinosa, is a unique combination of ingredients designed to help calm the bladder and support healthy functioning of the urinary tract system.† Each ingredient researched by Dr. Espinosa, a naturopathic physician specializing in urology, contributes to the health of the bladder glycosaminoglycan layer, nitric oxide production, healthy stress response, and normal mast cell production that helps promote a healthy functioning bladder and normal urine frequency.
Cysto Renew® is indicated for individuals who desire a healthy renewal and calming effect of the bladder.
For more information, check out our blog posts - This Is What Makes Cysto Renew The Best Support For Interstitial Cystitis and Brand Highlight - Douglas Labs.
| Serving Size: 4 Capsules | Amount/Serving |
| Chondroitin Sulfate | 600 mg |
| Quercetin dihydrate | 500 mg |
| L-Arginine | 250 mg |
| Bromelain | 160 mg |
| L-Citrulline | 150 mg |
| Proprietary Blend | 300 mg |
| Rhodiola rosea extract (root, standardized to 3% rosavins), Lemon Balm Extract (leaf), Aloe vera (inner leaf) |
Other Ingredients: Gelatin (capsule), cellulose, vegetable stearate, and silica.
Does Not Contain: Yeast, gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives, or flavoring.
Adults take 4 capsules daily or as directed by a healthcare professional.
Warning: No adverse effects have been reported. Keep out of reach of children.
Storage: Store in a cool, dry place, away from direct light.
The wall of the bladder is protected by a layer of molecules called proteoglycans, also called glycosaminoglycans (GAG). Underneath the GAG layer is a layer of cells called the urothelium. In certain bladder conditions such as IC, both of the layers can be disrupted. Once they are triggered by an insult in the bladder, they send the message on to the submucosa, the layer right behind the urothelial cells and very rich in nerves and mast cells. Activated mast cells release histamine and cytokines in the blood, which can lead to chronic bladder irritation.
Chondroitin sulfate is a proteoglycan and has been found on the surface of the bladder lumen. It is also a mast-cell inhibitor and can help contribute to the strengthening of the GAG layer to support healthy bladder integrity. Research has concluded that the bladder luminal and basal proteoglycans are associated with bladder function.
Quercetin is a bioflavonoid that has been positively shown in research to support bladder health by supporting the normal release of histamine from mast cells and basophils, and eliciting a healthy immune response. Bromelain is a proteolytic enzyme that plays a role in healthy systemic inflammation and cytokine balancing. It is often combined with Quercetin for favorable absorption and synergistic actions.
L-Arginine and L-Citrulline are both amino acids that are precursors to nitric oxide production, a substance that relaxes smooth muscles like those found in the bladder. Citrulline, an amino acid unrelated to citrus fruit, is synthesized in the body from arginine and ornithine and has been found to help relax blood vessels and release nitric oxide. Studies reveal that nitric oxide levels may be decreased in certain bladder conditions.
Bladders can be aggravated by stress and nerve signals. Rhodiola rosea is an herbal adaptogen that can support adrenal function and stress response. Lemon balm, despite its name, is not from lemon but is a perennial herb called Melissa officinalis that is related to the mint family. Lemon balm extract is considered to be a mild calming agent and helpful for stress support.!!Magnesium can help the muscles relax and function normally. Aloe vera leaf is a type of glucosaccharide that may assist in the formation of the GAG layer in the urinary tract system.
