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European Ash (Fraxinus angustifolia Vahl), a tree indigenous to Europe and the Near East and cultivated in North America for centuries, has long been used in the Mediterranean region for its support of digestive, urinary and hepatic systems. Now a standardized extract of European Ash seeds/fruits called Glucevia™ has demonstrated it can markedly reduce post-prandial glucose levels, support insulin sensitivity in liver and muscles, and support liver metabolism. It also helps increase hepatic and muscle uptake of simple
and complex sugars.
| Serving Size: 2 Vegetarian Capsules | Amount/Serving |
| Biotin | 8 mg |
| Chromium (as polynicotinate) | 500 µg |
| European Ash (Seed, Fruit) Extract (Glucevia™) | 500 mg |
| Berberine HCL | 500 mg |
| Milk Thistle (Seed) Extract (standardized to 70-80% Silymarin) |
300 mg |
| Resveratrol (as 98% pure trans-Resveratrol) | 250 mg |
Other Ingredients: Hydroxypropyl methylcellulose, magnesium stearate, silicon dioxide, microcrystalline cellulose, gum acacia.
As a dietary supplement, 2 capsules two times daily with food, or as directed by a healthcare professional.
Warning: Individuals with diabetes or related conditions should monitor blood glucose levels, as these ingredients may lower them. Not recommended during pregnancy. Breastfeeding women, and children should use only under the supervision of a healthcare professional. Discontinue use for 15 days before any lab test that uses (strept) avidin-biotin technology. Candidates include thyroid, cardiac, fertility, hormonal, bone metabolism, and other tests. Raised blood levels of biotin may interfere with results.
Store in a cool, dry place, tightly capped.
Glucevia™ is the only available extract of Fraxinus that is standardized to 10% nuzhenide and GI3, which have been shown in preclinical animal studies to increase the rate of glucose absorption in liver and muscle. Glucevia™ appears to be extremely safe. In these studies, as well as an earlier dosing study, there were no adverse effects or detrimental impacts on six clinical and 12 hematological parameters.
Berberine is a naturally occurring alkaloid found in goldenseal, Oregon grape, and barberry. It has been used for hundreds of years in Chinese and Ayurvedic medicine, as well as traditionally in the Middle East and Europe. Berberine has been found to help support normal healthy blood glucose within normal levels, including post-prandial glucose levels, glucose tolerance, and healthy insulin sensitivity. It has many other health benefits, including supporting and protecting liver function.
Chromium is a trace mineral which plays an essential role in normal carbohydrate metabolism and glucose tolerance. Chromium supports insulin receptor formation, insulin receptor phosphorylation, and insulin binding. The result is the potentiation of insulin and increased insulin sensitivity. Chromium may also support glucose tolerance by decreasing hepatic extraction of insulin. Chromium polynicotinate is the preferred form of chromium because Glucose Tolerance Factor (GTF) is generally considered to include chromium bound to nicotinic acid.
Milk thistle (Silybum marianum) has been used as a traditional liver supportive herb for more than 2,000 years. It was mentioned in the writings of the Greek healer Dioscorides, and Pliny the Elder. Milk thistle is native to Europe and was introduced into North America by the early colonists. It was utilized by the Eclectic physicians in the 19th century as well as by herbalists. The early United States Pharmacopeia listed a tincture of milk thistle. The main active component is the flavonoid complex silymarin. Besides its well-studied support for liver function, silymarin may help support healthy insulin function and blood lipids within normal levels. It may also help protect the pancreas.
Resveratrol is a hydroxystilbene found in red wine, nuts, grapes, pine trees, and certain vines, which appears to play a role in supporting healthy heart function. Preliminary evidence suggests it may also support healthy insulin sensitivity, and healthy blood glucose within normal levels.
Biotin, a B vitamin, is a necessary coenzyme for carboxylases involved with the synthesis of fatty acids from glucose, and glucose formation from proteins or fats. Preliminary evidence suggests that biotin and chromium in combination may support healthy blood glucose within normal levels, and normal, healthy peripheral circulation.
