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HMF Multi Strain Powder offers a comprehensive combination of 17 proprietary probiotic strains. Each convenient, once-daily serving provides 10 strains of Lactobacilli and seven strains of Bifidobacteria to promote colonization in both the small and large intestines. In one placebo-controlled trial, daily supplementation with HN019, a probiotic strain found in HMF Multi Strain Powder, promoted healthy intestinal transit time and reduced occasional constipation. Research suggests that HN019 may also help regulate immune cell activity to support a healthy immune system.
Similarly, HMF Multi Strain Powder contains CUL-60, CUL-21, CUL- 34 and CUL-20, which have been demonstrated in clinical trials to support intestinal comfort and promote a healthy microflora balance in the gastrointestinal tract. In addition to ex vivo evidence reporting that this probiotic combination can help regulate immune responses, daily supplementation with CUL-60, CUL-21, CUL- 34 and CUL-20 (plus vitamin C) was found to support upper respiratory tract health in schoolchildren. HMF Multi Strain Powder is a great alternative for adults and children who dislike or have difficulty swallowing capsules.
| Serving Size: 2 level scoops (1 g) | Amount/Serving |
| Probiotic Consortium | 16 billion CFU |
|
Lactobacillusacidophilus (CUL-60 & CUL-21), Bidobacterium animalis subsp. lactis (CUL-34) & Bidobacterium bidum (CUL-20), Lactobacillusacidophilus (NCFM®), Bidobacterium animalis subsp. lactis (HN019), Lactobacillus salivarius (CUL61), Lactobacillus rhamnosus (CUL-63), Lactobacillus gasseri (CUL-09), Bifidobacterium breve (Bb-18), Lactobacillus paracasei (CUL-08), Lactobacillus casei (CUL-06), Bidobacterium animalis subsp. lactis (CUL-62), Lactobacillus plantarum (CUL-66), Lactobacillus fermentum (CUL-67), Bifidobacterium longum (CUL-75), Bidobacterium longum subsp. infantis (Bi-26) |
Other Ingredients: potato maltodextrin.
In a glass, add water to 2 level scoops and mix. Take once daily or as recommended by your healthcare practitioner.
WARNING: If you are pregnant or lactating, have any health condition or are taking
any medication, consult your health professional before use. If you are
immunocompromised, consult your health professional before using probiotic-containing products. Keep out of the reach of children. Use only if safety seal is in tact.
Storage: Store in a cool, dry place.
Microflora Composition
In one randomized, double-blind, placebo-controlled trial, supplementation with HN019 significantly contributed to a favorable gut flora in aging adults. Elderly participants (over 60 years of age) consumed a placebo or one of three probiotic supplements daily for four weeks [low(6.5x x 10 CFU), medium (1.0 x 10 CFU) or high (5.0 x 10 CFU)]. Probiotic supplementation significantly increased the mean number of fecal Bifidobacteria when compared to baseline levels. As the levels of Bifidobacteria naturally decrease with age, supplementation with HN019 may represent an easy way to promote its proliferation in the intestines.
In addition, HN019 intake significantly increased Lactobacilli and Enterococci counts in the high and medium groups after four weeks. As Bifidobacteria produce acetate and lactate, they may also help to support the growth of Lactobacilli. This further demonstrated that daily supplementation with HN019 can contribute to a healthy gut flora composition in older adults.
Moreover, randomized, double-blind, placebo-controlled trials have reported that daily supplementation with a probiotic capsule containing CUL-60, CUL-21, CUL-34, and CUL-20 for approximately two or three weeks significantly promoted a healthy microflora balance in adults.
Intestinal Transit Time
Daily supplementation with HN019 also promoted gastrointestinal health as measured by improved whole gut transit time (WGTT) and gastrointestinal comfort and function scores. In this randomized, placebo-controlled trial, adults consumed either a placebo or probiotic capsule (1.8 billion CFU of HN019) daily for two weeks. Supplementation with HN019 was dose-dependently associated with a significant improvement in WGTT (25% and 33% decrease for the low-and high-dose groups, respectively). Probiotic supplementation also significantly improved both upper (abdominal comfort, gurgling) and lower (occasional constipation, bowel movement regularity and flatulence) gastrointestinal comfort and function scores. Combined supplementation with HN019 and NCFM® (a minimum of 10 CFU of each strain, plus 3.6 g of the plysaccharide polydextrose daily for two weeks) also significantly decreased colonic transit time when compared to a placebo in a randomized, double-blind, controlled study.
Genestra HMF's proprietary probiotics significantly reduced mild intestinal discomfort in an eight-week long, double-blind, randomized, placebo-controlled study. Participants consumed either a placebo or probiotic capsule (containing CUL-60, CUL-21, CUL-34 and CUL-20) once daily for eight weeks. In comparison with baseline values, probiotic supplementation significantly improved intestinal discomfort scores, including a 22% decrease in days with intestinal discomfort, 32% improvement in satisfaction with bowel habits and 30% improvement in quality of life scores. These improvements were also significantly greater when compared to placebo values.
Immune Health
Preclinical research has demonstrated that HN019 can promote healthy immune function, as measured by increases in the phagocytic activity of leucocytes and macrophages. Similar beneficial effects on immune cell activity have been observed in clinical trial involving elderly participants supplemented with HN019.In addition to the effects of individual strains on overall wellbeing, review evidence indicates that multi-strain probiotics may be more effective than single-strain supplements in supporting a diverse range of health outcomes.
Supplementation with a combination of Genestra GMF's proprietary probiotics and vitamin C helped to support respiratory immune health in schoolchildren. In this randomized, double-blind, placebo-controlled study, children consumed either a placebo or probiotic and vitamin C tablet (12.5 billion CFU of CUL-60, CUL-21, CUL-34, and CUL-20, plus 50 mg of vitamin C) once daily for six months. Compared with the placebo group, upper respiratory tract health and immune function was significantly better supported in children that received the probiotic and vitamin C supplement.
Similarly, supplementation with the same probiotic strains, plus 2 g of fructooligosaccharides was shown to significantly modulate cytokine production in a double-blind, place-controlled trail. Following the 12-week intake period, probiotics significantly mediated the production of IL-10, TGF-B, IL-1B and IL-6.
