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Allergy Research Group's Homocysteine Plus provides the primary nutrients known to be necessary for the breakdown of homocysteine into methionine and other metabolites, including vitamin B6 as pyridoxine and pyridoxal-5’-phosphate (P5P), vitamin B12 as methylcobalamin, folate as 5-methyltetrahydrofolate (5-MTHF), trimethylglycine (TMG), and L-serine.* It is enhanced with vitamin B2 as riboflavin-5-phosphate, Setria® glutathione, zinc, and increased amounts of activated pyridoxal-5’-phosphate.*
| Serving Size: 1 Capsule | Amount Per Serving |
| Vitamin B2 (as Riboflavin-5-Phosphate) | 10 mg |
| Vitamin B6 (50% as Pyridoxine Hydrochloride and 50% as Pyridoxal-5-Phosphate) | 30 mg |
| Folate (as 400 µg of 5-Methyltetrahydrofolate (from 740 µg [6S]-5-methyltetrahydrofolate acid, glucosamine salt)) | 667 µgDFE |
| Vitamin B12 (as Methylcobalamin) | 400 µg |
| Zinc Picolinate | 5 mg |
| Trimethylglycine | 500 mg |
| L-Serine | 100 mg |
| L-Glutathione (reduced) | 50 mg |
Other Ingredients: Hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, silicon dioxide.
As a dietary supplement, 1 capsule one or two times daily with meals, or as directed by a healthcare practitioner.
Normal homocysteine levels have been associated with cardiovascular and cognitive health, normal metabolism, and a healthy mood.* Homocysteine may affect all other methyl and sulfur group metabolism processes either directly or indirectly.
Homocysteine is metabolized from the essential amino acid methionine. To prevent excess homocysteine accumulation, the body can degrade it through two pathways of liver detoxification, transsulfuration and remethylation. The transsulfuration pathway requires both pyridoxine and P5P as well as serine, and the remethylation pathway can involve methylcobalamin, S-adenosyl-methionine (SAMe), 5-methyltetrahydrofolate, zinc, and trimethylglycine.
