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Ortho Molecular
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Cardiovascular Health
Alpha lipoic acid (ALA) is one of the most versatile antioxidants available. ALA's unique chemical properties allow it to support blood sugar balance already within normal levels and increase intracellular glutathione levels.
With its potent antioxidant properties, research has shown ALA strongly supports the neurovascular system and overall circulatory and blood vessel health. As a short-chain fatty acid, ALA can be absorbed by fatty tissues and maintain its solubility in water, allowing it to be easily excreted from the body when not needed. In addition, orally supplemented ALA readily crosses the blood-brain barrier after absorption in the small intestine. It then undergoes distribution via systemic circulation. Once inside the tissues, ALA can exert its antioxidant benefits both inside and outside the cells, including the cellular powerhouse, the mitochondria, where it functions as a coenzyme in several different biochemical pathways. ALA also serves as a sulfur donor, which allows it to support detoxification pathways that require sulfation.
Supportive of a wide variety of health-related issues, ALA recharges vitamin E, vitamin C, glutathione, and CoQ-10, and it directly quenches reactive oxygen species (ROS). Since it has water-soluble, fat-soluble, and sulfhydryl properties, it can be utilized by many different bodily tissues in a variety of ways. Its unique chemical properties allow ALA to support healthy blood sugar levels. This formulation of Lipoic Acid contains 300 mg of ALA and 300 mcg of biotin to prevent biotin depletion by absorption competition between the two vital antioxidants.
Key Benefits and Features:
| Serving Size: 1 Capsule | Amount/Serving |
| Biotin | 300 mcg |
| Sodium | 35 mg |
| Alpha Lipoic Acid (as R-Lipoic Acid) | 300 mg |
Other Ingredients: Hypromellose (Natural Vegetable Capsule), Microcrystalline Cellulose and Magnesium Stearate.
Does Not Contain: Gluten, corn, yeast, artificial colors, or flavors.
Take 1 capsule per day or as recommended by your health care professional.
Warning: If you are pregnant or nursing, consult your physician before taking this product. Keep out of the reach of children.
Storage: Keep tightly closed in a cool, dry place.
Blood Sugar Balance
In Germany, ALA has long been used to support neurovascular function. One of the many health benefits of lipoic acid is its ability to support insulin sensitivity by preventing oxidative damage resulting from blood sugar fluctuations. Additionally, lipoic acid is required for the cellular breakdown of carbohydrates and fatty acids. ALA supports blood vessel and circulatory health via its role in antioxidant regeneration. A randomized, controlled trial that looked at the effect of ALA on a measure of blood circulation showed that supplementing with 300 mg of ALA a day for four weeks improved blood flow by 44%.
At the molecular level, ALA supports blood sugar balance by activating an enzyme called adenosine monophosphate kinase (AMPK), a key regulator of cellular energy.4 AMPK coordinates both long-term and short-term metabolic changes, improving energy production and reducing energy storage. The compound activates cellular metabolism by improving insulin sensitivity, down-regulating genes involved in fat anabolism, and activating genes involved with fat catabolism for ATP production. A three-month study using a dose of 600 mg/ day of ALA demonstrated a 36% reduction in blood fats and a 38% improvement in oxidative stress. An additional placebo-controlled trial on the effects of ALA on 74 subjects found that 600 mg of ALA per day significantly enhanced glucose transport and utilization.
Eye Health
Lipoic acid has also been used to support eye health. Lipoic acid, at 150 mg per day for one month, was found to improve visual function in patients with severe free radical stress of the eyes.
