Douglas Laboratories Metabolic Rejuvenation
Metabolic Rejuvenation® is a comprehensive 28-day, 3-phase detoxification support program with nutrients specifically chosen to prepare the body for elimination, phase 1 and 2 liver detoxification, and renewal of the body and intestinal tract. One Metabolic Rejuvenation® box includes 4 bottles (one for each week) with convenience packs.
Suggested Usage: As a dietary supplement, adults take 1 pack twice daily with 8 ounces of purified water or as directed by your healthcare professional
Week 1 - take 1 pack twice daily
Week 2 and 3 - take 1 AM and 1 PM pack daily
Week 4 - take 2 packs daily
Week 1- Prepare
The goal of the first week is to open pathways for elimination and prepare the body to properly detoxify in the next phase. The proprietary blend supplies fibers from pectin, glucomannan, and slippery elm bark to naturally stimulate the bowel, and may contribute to immobilizing unwanted compounds in the gastrointestinal tract. Magnesium citrate may also support regular bowel movements.
Week 2 and 3 - Detox
The goal of weeks 2 and 3 is to support phase 1 and phase 2 detoxification of the liver. As the body’s main detoxification organ, the liver is responsible for removing all potentially harmful molecules. This detoxification process occurs in 2 phases. The supplements in week 2 and 3 convenience packs help to maintain liver structure and function in response to environmental toxins. Isothiocyanates (ITCs) found in Wasabia japonica are naturally occurring compounds that have the ability to stimulate liver detoxification pathways. Sulforaphane in broccoli extract has been found to increase the activity of Phase II enzymes. For efficient Phase 2 detoxification, the liver cells require sulphur-containing amino acids such as taurine, methionine and cysteine. As a biologically active precursor for glutathione synthesis, N-Acetyl-L-cysteine raises intracellular glutathione levels. L-Glutathione scavenges toxic free radicals and inhibits peroxidation by slowing down free-radical catalyzed chain reactions. Glutathione is involved in DNA synthesis and repair, protein and prostaglandin synthesis, amino acid transport, metabolism of toxins and carcinogens, immune system function, prevention of oxidative cell damage, and enzyme activation. Dietary sulfur assumes a major role in detoxification as part of the hepatic sulfur conjugation pathways. Glutathione, sulfur and NAC support mercury detoxification. High mercury in the body can inhibit antioxidant enzymes and deplete intracellular glutathione. B vitamins, vitamin C and lipoic acid perform as antioxidants to scavenge free radicals. Silymarin supports healthy levels of glutathione and superoxide dismutase, two primary substances with antioxidant activity in the liver that reduce free radicals known to interfere with normal cell function. Garlic appears to prevent endothelial cell depletion of glutathione, which may be responsible for its antioxidant effects. Extracts of artichoke, Cynara scolymus, can help stimulate the flow of bile from the liver and support liver cells from oxidative damage. Cynara’s usefulness in liver health is thought to be due to its content of caffeoylquinic acids, e.g. cynarin, and flavonoids. Lipopolysaccharide (LPS) triggers excessive secretion of a variety of mediators including nitric oxide (NO) and prostaglandin E2 (PGE2). Luteolin and luteolin-7-O-glucoside, the active compounds with antioxidant activity from dandelion extract, may support cellular protection and reduce lipopolysaccharides in animal models.
Week 4- Renew
The goal of week 4 is to replenish lost nutrients through the detoxification phase and provide specific nutrients to help support the gut microflora and metabolism. A multivitamin/mineral with phenolic proprietary blend provides adequate amounts of vitamins, minerals, and antioxidants to nutritionally replenish the body. Omega-3 fatty acids from fish oil support hormone production and optimal lipid ratio. Glutamine helps maintain normal intestinal permeability, as well as mucosal cell regeneration and structure, especially during periods of physiological stress. Glutamine also carries potentially toxic ammonia to the kidneys for excretion, which helps maintain normal acid-base balance. Healthy bacteria in the intestinal tract can be removed during extensive or frequent bowel elimination, thereby making supplementation with probiotic bacteria cultures necessary after a detoxification regimen. A normal intestinal microflora rich in lactobacilli creates acidic conditions that are unfavorable for the settlement of undesirable microorganisms.
WARNING: This product can expose you to lead, which is known to the
State of California to cause birth defects or other reproductive harm. For
more information go to www.P65Warnings.ca.gov/food