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Gastrointestinal Health
Ortho Spore IG™ is a spore-based, broad-spectrum probiotic formula designed to promote a healthy gut microflora, protect mucosal integrity, and relieve small intestinal bacterial overgrowth (SIBO). Uniquely included in this formula are serum-derived bovine immunoglobulins that bind to and eliminate microbes and toxins that are common in SIBO.
SIBO is a condition that occurs when there is an overabundance of commensal bacteria from the colon present in the small intestine. The health of the small intestines relies on balanced microbiota, and probiotics and immunoglobulins can contribute to that balance by having a positive influence on the intestinal environment, including pH, organism diversity, and immune signaling.
Probiotics have been extensively studied and are characterized as having broad GI and immune benefits. Probiotics are live organisms and must be shelf-stable through the expiration date, so they can be precisely delivered to the intestinal tract to have maximum benefit. Bacillus spores remain dormant in harsh environments until they reach more favorable environments like the human gastrointestinal tract. The combination of specific strains, particularly Bacillus coagulans, Bacillus clausii, and Bacillus subtilis, relieves symptoms for common GI complaints and reinforces healthy gut function.
In the search for innovative ways to improve microbiome diversity, we have combined our blend of spore-forming probiotics alongside immunoglobulins uniquely shown to bind to bacteria and toxins, driving immune response. IgG helps to maintain a healthy intestinal immune system by binding a broad range of microbes and toxins within the gut lumen.
Key Benefits and Features:
For more information, check out our blog post - What I Wish I Knew About These Soil-Based Probiotics.
| Serving Size: 3 Capsules | Amount/Serving |
| Calories | 5 |
| Total Carbohydrate | <1 g |
| Protein | 1 g |
| Sodium | 5 mg |
| Serum-Derived Bovine | 1 g |
| Immunoglobulin Protein Isolate (ImmunoLin) | |
| Immunoglobulin G (IgG) | 480 mg |
| Bacillus coagulans (MTCC5856_ (LactoSpore) | 12 mg (2 Billion CFU++) |
| Bacillus clausii (CSI08) | 3 mg (1 Billion CFU++) |
| Bacillus subtilis (DE111) | 3 mg (1 Billion CFU++) |
Other Ingredients: Hypromellose (Vegetable Capsules), Rice Maltodextrin, and Medium Chain Triglycerides.
Does Not Contain: Gluten, artificial colors, or flavors.
++Colony Forming Units
Take 3 capsules per day or as recommended by your health care professional.
Warning: If you are pregnant or nursing, consult your physician before taking this product. Keep out of the reach of children.
Storage: Keep tightly closed in a cool, dry place.
Bacillus coagulans
B. coagulans has been shown to increase the commensal GI microbiota. Supplementation of 1 billion CFU daily for 28 days with B. coagulans significantly increased levels of the commensal microbe F. prausnitzii from baseline compared to placebo, as well as increased Bacillus spp. in fecal samples of adults over 65.5 B. coagulans has also been shown to relieve GI discomfort and improve stool consistency. B. coagulans given once a day for eight weeks showed reduced daily bowel movements and GI symptoms. B. coagulans also significantly improved bowel movements in healthy adults with occasional constipation, as well as decreased abdominal discomfort.
Bacillus clausii
B. clausii is commonly used as a probiotic to promote balance in the microbiome and has shown promising results in individuals with SIBO specifically. B. clausii has demonstrated significant effectiveness in adults with acute diarrhea. B. clausii has also been shown to significantly reduce the duration of occasional diarrhea and decrease stool frequency in children.
Bacillus subtilis
B. subtilis has been shown to relieve GI distress in patients. B. subtilis supplementation of 1-3 billion CFU alongside motility-stimulating agents was shown to be effective for relief of GI symptoms at four weeks.
Serum-Derived Bovine Immunoglobulins
Probiotics are a natural choice for supporting beneficial bacteria in the gut, but supplementation to eliminate unwanted microbes should also be considered. Within the gut barrier, researchers found that the binding capabilities of immunoglobulins have a positive effect on gut barrier function in vitro. Broad-spectrum binding capabilities (See Table 1) demonstrate the positive influence of serum-derived bovine immunoglobulins. This binding and elimination decreases microbe and toxin encounters by the immune system and resets immune tolerance.





