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Ortho Molecular
products.
Cardiovascular HealthÂ
Orthomega® Select DHA is a powerful omega-3 concentrate that provides targeted support to maintain healthy blood pressure levels and boosts cognitive function and healthy brain development.
Orthomega® Select DHA is a high-concentration docosahexaenoic acid (DHA) fish oil formula for those needing intensive nutritional support from this essential fatty acid. DHA is a fatty acid well-known for its role in cardiovascular and cognitive health and boosting mood, memory, and focus. It is sourced from waters off the Chilean coast, where cold, fresh waters provide the cleanest, most sustainable source of fish in the world. Each soft gel delivers 580 mg of DHA in the natural triglyceride form for superior absorption. This high-concentration DHA fish oil is purified, vacuum-distilled, and independently tested to ensure heavy metals, pesticides, and polychlorinated biphenyls (PCBs) are removed to undetectable levels.
Key Benefits and Features:Â
| Serving Size: 1 Soft Gel Capsule | Amount/Serving |
| Calories | 15 |
| Total Fat | 1.5 g |
| Cholesterol | 5 mg |
| DHA (Docosahexaenoic Acid)Â | 580 mg |
| EPA (Eicosapentaenoic Acid)Â | 130 mg |
Other Ingredients: Fish Oil (anchovy, jack mackerel, mackerel, and sardine) (Highly Refined and Concentrated Omega-3), Gelatin, Glycerin, Water (Purified), Natural Flavors, Natural Tocopherols, Rosemary Extract (Leaf), and Ascorbyl Palmitate.Â
Does Not Contain: Gluten, corn, yeast, artificial colors, or flavors.
Take 1 soft gel capsule per day or as recommended by your health care professional.
Warning: If you are pregnant or nursing, consult your physician before taking this product. Keep out of the reach of children.
Storage: Keep tightly closed in a cool, dry place.Â
Fish Oil Delivery – Triglycerides vs. Ethyl Esters
While the amount of EPA and DHA provided in a fish oil product is important for efficacy, the type of fish oil delivered is another significant factor in defining fish oil effectiveness. The human body is accustomed to digesting and absorbing EPA and DHA in the natural triglyceride form. Â Even though triglyceride-based fish oils are the preferred form for superior fish oil absorption, due to cost, the vast majority of fish oil products available on the market are packaged in semi- synthetic ethyl ester form. While less expensive, their unusual structure is resistant to the digestive enzymes that enable fat breakdown. In a study comparing EPA and DHA digestion in both the natural triglyceride and ethyl ester form, five common digestive lipase enzymes were shown to more easily digest fish oil in the natural triglyceride form as compared to the ethyl ester substrate. A review of the existing literature has shown that fish oil provided in the natural triglyceride form is more efficiently digested and is 70% more absorbable than the ethyl ester form.
Omega-3 Depletion
An accumulating body of research shows that the typical modern diet does not provide a sufficient amount of omega-3s for optimal health. Â Symptoms of general omega-3 deficiency are common and often overlooked. These symptoms may include dry, itchy, or flaky skin, poor sleep quality, poor circulation, eye discomfort, and mood imbalance.
Cardiovascular Health
DHA has been found to have positive effects on key aspects of cardiovascular health, including balancing blood lipids, stabilizing cardiac function, and increasing relaxation of arteries to help support normal blood pressure levels. Mori et al. have reported that 4 g/day of DHA has a significant impact on arterial health and helps to maintain healthy blood pressure levels. Additionally, cerebrovascular health has been found to be protected by optimal levels of phospholipid DHA, indicating that sufficient amounts of DHA support brain circulatory health. In a systematic review of 11 randomized, controlled trials published between 1996 and 2011 that analyzed the association between DHA and changes in the concentration of blood fat profile components, DHA supplementation was found to maintain healthy blood lipid levels and increase levels of good fats in people with cardiovascular concerns. DHA—but not EPA—has also been found to enhance dilation of the arteries by decreasing the release of calcium within smooth muscle that causes arterial constriction.  This novel mechanism of action makes DHA the omega-3 fatty acid of choice for those with blood pressure concerns.
Ocular and Cognitive Health
The retina is a specialized portion of the nervous system that has one of the highest levels of long-chain fatty acids in the human body, and it is especially high in DHA. Research has shown that children supplemented with DHA (115 mg/day) from six months to one year of age had significantly improved visual acuity than children in the control group; in adults, fish and DHA intake reduce age-related visual concerns. Patients with retinal concerns have been found to have lower levels of DHA, partly due to reduced activity of delta-5desaturase, an enzyme responsible for increasing essential fats in the body. In addition, 1,200 mg/day of DHA increased the positive effects of vitamin A in those with visual challenges.16 Increased dietary intake of fish and DHA—but not EPA—has also been correlated with better cognitive health.
Maternal and Infant Health
Research has confirmed that maternal fatty acid levels, especially DHA levels, steadily drop in late pregnancy, increasing risk for postpartum mood changes. Rapid growth in the brain occurs during the last trimester of pregnancy and the first several postnatal months; therefore, the need for maternal DHA is critical during these months for brain development. In addition, a meta-analysis of 41 studies showed that lower fish consumption and breast milk DHA content were associated with increased risk for low mood after pregnancy. Several reports suggest that maternal supplementation of fish oils or DHA alone during the third trimester and while breastfeeding can improve cognitive development in newborns, improve sleep patterns, and even increase IQ scores at age four.
