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Ortho Molecular
products.
Cardiovascular Health
Orthomega® Select EPA is a powerful omega-3 concentrate that supports a positive mental outlook, inflammatory balance, cardiovascular health, and blood sugar balance already within normal levels. It also provides high-intensity support for joint comfort and musculoskeletal integrity.
Orthomega® Select EPA is a high-concentration eicosapentaenoic acid (EPA) fish oil designed for those needing intensive nutritional support of this essential fat. Research shows that EPA promotes a positive mental outlook and has a significant calming effect on the brain. In addition, EPA has been shown to improve joint mobility and support cardiovascular health. Orthomega® Select EPA is sourced from off the Chilean coast, where cold, fresh waters provide the cleanest, most sustainable source of fish in the world. Each soft gel delivers 660 mg of EPA in the natural triglyceride form for superior absorption.
While EPA/DHA combination formulas remain the backbone of any fish oil regimen, as research on fish oil continues to accumulate, new evidence has emerged supporting the value of unique formulations of high-intensity EPA for more targeted uses. Fatty acids in the n-3 family are considered essential to humans because our bodies are unable to make them; in humans, conversion of alpha linolenic acid to EPA is slow, making supplementation necessary. EPA also boosts cognitive health and is an essential part of the structural integrity of the central nervous system, making it a key component of neurological wellness. With over 10,000 published studies on fish oil in the last three decades, EPA and DHA from fish oil are among the most researched natural ingredients available and have a long history of safety and efficacy.
Key Benefits and Features:
| Serving Size: 1 Soft Gel Capsule | Amount/Serving |
| Calories | 15 |
| Total Fat | 1.5 g |
| Cholesterol | 5 mg |
| EPA (Eicosapentaenoic Acid) | 660 mg |
| DHA (Docosahexaenoic Acid) | 60 mg |
Other Ingredients: Fish Oil (anchovy, jack mackerel, mackerel, and sardine) (Highly Refined and Concentrated Omega-3), Gelatin, Glycerin, Water (Purified), Natural Flavors, Natural Tocopherols, Rosemary Extract (Leaf), and Ascorbyl Palmitate.
Does Not Contain: Gluten, corn, yeast, artificial colors, or flavors.
Take 1 soft gel capsule per day or as recommended by your health care professional.
Warning: If you are pregnant or nursing, consult your physician before taking this product. Keep out of the reach of children.
Storage: Keep tightly closed in a cool, dry place.
Fish Oil Delivery – Triglycerides vs. Ethyl Esters
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. While the amount of EPA and DHA provided in a fish oil product is important for efficacy, the type of fish oil delivered is another significant factor in defining fish oil effectiveness. The human body is accustomed to digesting and absorbing EPA and DHA in the natural triglyceride form. Even though triglyceride-based fish oils are the preferred form for superior fish oil absorption, due to cost, the vast majority of fish oil products available on the market are packaged in semi- synthetic ethyl ester form. While less expensive, their unusual structure is resistant to the digestive enzymes that enable fat breakdown. In a study comparing EPA and DHA digestion in both the natural triglyceride and ethyl ester form, five common digestive lipase enzymes were shown to more easily digest fish oil in the natural triglyceride form as compared to the ethyl ester substrate. A review of the existing literature has shown that fish oil provided in the triglyceride form is more efficiently digested and is 70% more absorbable than the ethyl ester form.
Omega-3 Depletion
An accumulating body of research shows that the typical modern diet does not provide a sufficient amount of omega-3s for optimal health. Insufficient conversion within the body of alpha linolenic acid (ALA) to the active EPA and DHA may reduce the amount available for use in organs and tissues. Symptoms of omega-3 deficiency are common and often overlooked. These may include dry, itchy, or flaky skin, poor sleep quality, poor circulation, eye discomfort, and mood imbalance. Low levels of EPA have been linked with mood imbalance, cognitive impairment, and neuropathy.
Mood Balance
Long-chain n-3 fatty acids, such as EPA, are important components of membranes within neurological organs and tissues. They affect membrane fluidity and influence synaptic function and possibly serotonin and dopamine metabolism. In several studies, fish consumption has been directly linked to decreased risk of low mood, especially in women, and several clinical trials have used n-3 fatty acids to promote a positive mental outlook. Studies to date have shown that 1 g of EPA improves low mood scores in patients.9 Among a similar population, 2 g/day of a comparable preparation had a highly significant improvement in mood scores. Previous reports suggest there is a link between low EPA levels and the most extreme signs of a negative mental outlook.
Additional evidence indicates that supplementation with long-chain n-3 polyunsaturated fatty acids (PUFAs) could be beneficial in the treatment of some individuals with irritability and aggressive tendencies. Another double-blind, randomized trial found that patients who received EPA for three months showed an increase in sense of calmness, while this was not seen in patients who received placebos. Calmness scores remained significantly higher in the EPA group for three months after supplement discontinuation.
Joint Discomfort and Inflammatory Balance
EPA is capable of forming eicosanoids, which function to counteract the activity of eicosanoids derived from arachidonic acid, a mechanism known to maintain normal inflammatory balance. Numerous studies point to the key role of EPA in improving joint discomfort and promoting musculoskeletal strength. EPA has also been found to safely support neck and back discomfort from physical activity and overexertion.
Cardiovascular Health and Blood Sugar Metabolism
Several large, randomized clinical trials have proven the benefits of EPA for cardiovascular health. EPA has been found to diminish oxidative stress and promote cardiomyocyte strength, and an eight-week-long usage of EPA resulted in a significant percentage reduction of C-reactive protein levels. EPA has also been shown to support blood sugar balance already within normal levels. Supplementation with EPA has been shown to support blood sugar balance and related markers.
