PhosChol: A Membrane Therapeutic for the Liver
According to the intensity of exposure to noxae, malnutrition or viruses, liver damage may manifest itself as:
- acute and chronic hepatitis
- fatty liver
- liver cirrhosis
PPC is a superior protectant against liver damage. Irrespective of the origin, damage to liver cell membranes and to their organelles is generally present in hepatopathies. Metabolic functions of the liver cell and the activity of enzymes bound to membranes are inhibited, thus causing the clinical picture of liver disorders.
PhosChol: Heart Health
PhosChol's primary active ingredient is PPC. Clinical studies have shown that PPC can help bring the lipid profile into the normal range.
HDL particles containing PPC, transport 50% more cholesterol than native HDL particles.
(ZIERENBERG,O. et al: Atherosclerosis 39, 1981, 527)
PhosChol: For Diabetes
PhosChol's primary active ingredient is PPC. In clinical studies, PPC has been shown to have positive effects on plasma lipids and plasma lipoproteins. Moreover, PPC has been shown to contribute to an improved condition of blood glucose, glycosylated hemoglobin, ketone body excretion, and other diabetes-specific parameters by positively affecting the pathological mechanism of specific diabetes-associated disturbances.
As a Membrane Therapeutic, PPC has been shown to be a valuable supplement to the basic treatment of diabetics with insulin or oral anti-diabetics if controlling the diabetes does not lead to a restoration of normal lipid metabolism.
PPC has been shown to:
- Have positive affects on plasma lipids and plasma lipoproteins
- Improve the lipoprotein profile in diabetic patients
- Influence reverse cholesterol transport to the liver and may help reduce the consequences of hyperlipidemia
- Have positive decreasing effects in some patients to the sensitivity rate of peripheral tissues to insulin
- Have positive effects on incipient peripheral gangrene
- Protect the liver structures against modification by the aldehydic form of glucose
- Reduce signs of liver damage due to diabetic related tuberculosis
- Cause positive increases in plasma lipid levels in the origin of degenerative vascular complications of diabetes
- Normalize the energy and lipid metabolism in the liver cell mitochondria
- Hypo-LPE effects of PPC were observed in decreasing blood cholesterol and triglycerides
- Protects the insulin-producing pancreatic cells
Indication: Diabetes-associated dyslipidemia that cannot be completely normalized by insulin or oral antidiabetics, particularly hypertriglyceridemia and hypoalpha-lipoproteinemia; diabetes-induced peripheral, coronary and cerebral circulation disturbances.
PhosChol: Age Related Memory Loss and Enhanced Brain Function
There is evidence that PPC is important for brain health throughout one's life.
PPC is critical for proper development of important brain areas, including the hippocampus, in fetuses and infants.
A study involving college students demonstrated that choline improved memory and cognitive skills. PhosChol provides the body with a preferred source of choline.
PPC may be especially important in advanced age because the brain of an older adult takes less choline into the brain than that of a younger adult. The decrease of PPC in the brain may play a role in developing age related memory loss, and perhaps Alzheimer's Disease.
PhosChol: Gastrointestinal Health
The surface of the stomach, known as the mucosal, protects the stomach wall from the high concentrations of acid and the enzymes present in the stomach's contents. Without this protection, the stomach wall would be digested along with the food suspension that the stomach contains.
The PPC in PhosChol
- Is integrated in the gastric mucosa
- Significantly lowers ulceration under treatment by Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
- May relieve pain of patients suffering from stomachache
Is a natural way to protect the stomach against exogenous damaging substances like over-the-counter (OTC) and prescription pain killers, also referred to as NSAIDs
- May reduce symptoms and improve quality of life
- Is a preventive nutritional food supplement for daily use
- Several European and American research groups have been able to show that PPC, particularly when it has a high content of essential fatty acids, can help heal gastric erosions.
PPC is an Essential Component of the Mucosal
Phospholipids, especially PPC, are essential components of the mucosa. Disorders leading to a reduction in the PPC content, or a disruption of the PPC membrane cause pain, or in more severe forms, gastric ulcers or cancer. Disturbances are caused by the following factors: stress, alcohol, beverages that are too cold, incorrect diet, post gastrointestinal operations, and reflux of bile from the intestine into the stomach, which destroy the PPC membrane and, hence, the protective film. Some pain medication often referred to as non-steroidal anti-inflammatory drugs (NSAIDs) can also cause significant erosion. NSAIDs include many prescription pain medications and other over the counter products such as ibuprofen, naproxyn, or antirheumatics such as aspirin.