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Allergy Research Group® Pregnenolone is micronized in a lipid base: the pregnenolone is reduced in size to tiny crystals, and stabilized in a lipid matrix. This advanced system results in a product with optimized absorption characteristics.* Allergy Research Group® Pregnenolone is soyfree, and uses the plant wild yam as a starting material (non-GMO, nonirradiated, and non-ethylene-oxide-treated).
| Serving Size: 1 Tablet |
Amount Per Serving |
| Pregnenolone | 100 mg |
Other Ingredients: Micosolle®, microcrystalline cellulose, vegetable oil, vegetable wax, Cab-o-sil®, magnesium stearate, vitamin E.
As a dietary supplement, 1 tablet daily with a meal, or as directed by a healthcare professional.
The Micronized Lipid Matrix tablet system allows pregnenolone to be directly presented to the systemic circulation via the lymph. The lipid matrix protects the micronized pregnenolone crystals, which are less than 50 microns in size, from the harsh gastric juices, and then allows them to be absorbed via the lymph. By avoiding the hepatic portal vein and the liver ‘first-pass effect’, higher levels of pregnenolone are available, for a longer time period.* Preparations (micronized or non-micronized) that do not use the Lipid Matrix system must first go through the portal vein system.
Pregnenolone is a naturally occurring metabolite of cholesterol that acts as a precursor to all adrenal cortical steroids, including progesterone, testosterone, dehydroepiandrosterone, dihydrotestosterone, aldosterone, cortisol, and estradiol. The body produces pregnenolone from cholesterol in the mitochondria through the cytochrome P450 conversion system. The brain requires pregnenolone, producing it and also absorbing more from the blood.
