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Multivitamin/Mineral Formula Targeting Common Genetic Polymorphisms to Support Daily Wellness
PureGenomics® Multivitamin is a once-daily multivitamin/mineral formula designed to address the nutrient requirements associated with common genetic variations. Activated B vitamins, including pyridoxal-5- phosphate, riboflavin-5-phosphate, and the enhanced-retention thiamin derivative, benfotiamine. Methylation plays many roles, including neurotransmission, DNA synthesis, and gene regulation. Riboflavin is an essential cofactor for MTHFR, a genetically polymorphic enzyme that supports the methylation of homocysteine and other substrates as part of the methylation pathway.
Key Benefits and Features:
| Serving Size: 1 Vegetarian Capsule | Amount/Serving |
| Vitamin A (as vitamin A acetate and 27% beta carotene) | 1,125 mcg |
| Vitamin C (as ascorbic acid) | 180 mg |
| Vitamin D (as cholecalciferol) (D3) | 25 mcg (1,000 IU) |
| Vitamin E (as d-alpha tocopherol succinate) | 20 mg |
| Vitamin K (as vitamin K1) | 60 mcg |
| Thiamin (as thiamin HCI) (B1) | 3 mg |
| Riboflavin (as vitamin B2 and 43% riboflavin 5' phosphate (activated B2)) | 3 mg |
| Niacin (as niacinamide) | 20 mg |
| Vitamin B6 (as pyridoxine HCI and 38% pyridoxal 5' phosphate (activated B6)) | 4 mg |
| Folate (as Metafolin, L-5-MTHF) | 1,333 mcg DFE (800 mcg L-5-MTHF) |
| Vitamin B12 (as adenosylcobalamin and 50% hydroxycobalamin) | 1,000 mcg |
| Biotin | 300 mcg |
| Pantothenic acid (as calcium pantothenate) (B5) | 10 mg |
| Choline (as choline bitartrate) | 56 mg |
| Iodine (as potassium iodide) | 150 mcg |
| Zinc (as zinc citrate) | 25 mg |
| Selenium (as selenomethionine) | 70 mcg |
| Manganese (as manganese citrate) | 2 mg |
| Chromium (as chromium polynicotinate) | 200 mcg |
| Molybdenum (as TRAACS molybdenum glycinate chelate) | 75 mcg |
| Vitamin K2 (as menaquinone-7) | 20 mcg |
| BenfoPure benfotimaine | 3 mg |
| Boron (as boron glycinate) | 1 mg |
| Inositol | 25 mg |
| FloraGLO lutein | 3 mg |
| Zeaxanthin | 500 mcg |
Other Ingredients: Vegetarian capsule (cellulose, water), trimagnesium citrate, and ascorbyl palmitate.
Does Not Contain: Wheat, soy, dairy, eggs, artificial colors, artificial sweeteners, coatings, shellacs, GMOs, tree nuts, peanuts, sesame, unnecessary binders, fillers, preservatives, magnesium stearate, gluten, trans fat, and hydrogenated oils.
Gluten Free, Non-GMO, Vegetarian
As a dietary supplement, take 1 capsule daily, with a meal.
Warning: Vitamin K may be contraindicated with Coumadin (Warfarin). If you are pregnant or lactating, or have any health condition, or are taking any medication, consult your health professional before use.
Storage: Store in a cool, dry place.
Individuals with the rs1801133 TT variant exhibited enhanced cardiovascular benefits from supplemental riboflavin in multiple clinical trials. Since the MTHFR T allele also reduces the activation of folate to L-5methyltetrahydrofolate (L-5-MTHF), this formula provides 800 mcg of Metafolin® (L-5-MTHF), a naturally occurring, universally metabolized form of folate that does not require MTHFR for activation.
PureGenomics® Multivitamin provides vitamin B12 as a blend of adenosylcobalamin and hydroxycobalamin to support both mitochondrial function and methylation. Choline is a critical methyl donor that plays important roles in neuronal maintenance and cognitive function. Certain genetic variations in MTHFR and PEMT, enzymes that play critical roles in methylation and choline synthesis, respectively, have been associated with increased dietary choline needs. Since many genetic variations influence vitamin D metabolism, transport, and receptor function, PureGenomics® Multivitamin provides 25 mcg (1,000 IU) vitamin D to support optimal dietary intakes.
Pre-formed vitamin A is also included to allow efficient assimilation of retinol in individuals with BCMO1 polymorphisms, which may reduce the conversion of beta-carotene to active vitamin A. Lutein and zeaxanthin are included to support macular and retinal health.
