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Eases Soreness and Supports Joint Health in as Little as 2 Weeks
Your body naturally produces specialized pro-resolving mediators (SPMs) to ease soreness and support recovery, but SPM levels decline with age. SPM Active® One Daily replenishes what your body needs: concentrated SPMs derived from omega-3 fish oil, formulated to target the root causes of soreness.
The result is less joint discomfort, faster bounce-back after activity, and support for long-term joint health, all in one convenient softgel per day. Feel less sore in as little as 2 weeks.
Key Benefits and Features:
Also available in a smaller, twice-daily dose, SPM Active.
| Serving Size: 1 Softgel | Amount/Serving |
| Calories | 10 |
| Total Fat | 1 g |
| Cholesterol | <5 mg |
| Active Fractioned Marine Lipid Concentrate | 1 g |
| SPM content standardized to: | |
| 18-hydroxy-eicosapentaenoic acid (18-HEPE) | |
| 17-hydroxy-docosahexaenoic acid (17-HDHA) | |
| 14-hydroxy-docosahexaenoic acid (14-HDHA) |
Other Ingredients: Fractioned marine lipid concentrate [fish oil (anchovy, sardine, and mackerel) and mixed tocopherols (antioxidant)], softgel shell (gelatin, glycerin, and water), and silica.
Contains: Fish (anchovy, sardine, and mackerel).
Non-GMO, Gluten Free, Sugar Free, lactose Free
Take one softgel once daily or as directed by your healthcare practitioner.
Warning: If pregnant, nursing, or taking medications, consult your healthcare practitioner before use. Keep out of the reach of children.
Storage: Keep tightly closed in a cool, dry place.
The Science Inside SPM Active® One Daily
Your body naturally produces specialized pro-resolving mediators (SPMs) to help ease soreness and support recovery. But over time, our SPM levels drop, and muscle and joint discomfort start to add up.
SPM Active® One Daily gives your body more of what it needs in just one softgel per day. These natural compounds from omega-3 fish oil help your body ease soreness rather than simply masking symptoms.
What to expect with consistent use:
Specialized Pro-Resolving Mediators (SPMs) — Natural compounds that help your body target the root cause of soreness and support lasting joint health.
How Are SPMs Different from Traditional EPA/DHA Omega-3 Fish Oils?
Most fish oils supply EPA and DHA, which your body then has to convert into SPMs. SPM Active® One Daily skips that step. It delivers bioactive omega oils with specialized pro-resolving mediators (SPMs) already pre-converted and ready to work, supporting your body's natural recovery process more efficiently.
The result: targeted relief that helps ease minor joint discomfort, support immune balance, and speed up recovery after physical stress or exercise.
SPM Active® One Daily is clinically tested to help you feel less sore in as little as 14 days. As we age, natural SPM production declines. This formula helps replenish those levels so your body can bounce back.
For over 40 years, Metagenics® has led innovation in health supplements, exceeding industry standards for transparency and accountability. Metagenics guarantees that what’s on the label is what’s in the bottle, and that commitment is why they're trusted by more than 50,000 healthcare providers worldwide. This, and all their formulas, are also:





