Douglas Laboratories Tri-B-100
Tri-B-100 is a six to eight hour timed release formulation of all the B vitamins as well as several other important dietary components metabolically associated with the B vitamins.
Each serving contains:
Thiamine - 100 mg
Riboflavin - 100 mg
Niacinamide - 100 mg
Vitamin B6 (as Pyridoxine HCl) - 100 mg
Folic Acid - 400 mcg
Vitamin B12 (as Cyanocobalamin) - 100 mcg
Biotin - 100 mcg
Pantothenic Acid (as Calcium Pantothenate) - 100 mg
Choline Bitartrate - 100 mg
Inositol - 100 mg
PABA (para-Aminobenzoic Acid) - 100 mg
Other ingredients: Cellulose, ethylcellulose, dicalcium phosphate, stearic acid, vegetable stearate, and silica.
As a dietary supplement, adults take 1 tablet daily or as directed by your healthcare professional.
As co-enzymes, the B vitamins are essential components in most major metabolic reactions. They play an important role in energy production, including the metabolism of lipids, carbohydrates, and proteins. B vitamins are also important for blood cells, hormones, and nervous system function. As water-soluble substances, B vitamins are not generally stored in the body in any appreciable amounts (with the exception of vitamin B-12). Therefore, the body needs an adequate supply of B vitamins on a daily basis.
Thiamin, riboflavin, and niacin are all essential coenzymes in energy production. Thiamin is converted quickly into thiamin pyrophosphate, which is required for glycolytic and Krebs cycle reactions. Thiamin also appears to be related to nerve impulse transmission. Riboflavin is a component of the coenzymes FAD and FMN, which are intermediates in many redox reactions, including energy production and cellular respiration reactions. Niacin is also a component of the coenzymes NAD and NADP, which are involved in energy production, as well as biosynthetic processes.
Vitamin B-6 is a coenzyme in amino acid metabolism. It is necessary for the metabolism of homocysteine and the conversion of tryptophan into niacin. Vitamin B-6 dependent enzymes are also needed for the biosynthesis of many neurotransmitters, including serotonin, epinephrine, and norepinephrine. Vitamin B-12 and folic acid are coenzymes in DNA and RNA metabolism. Both of these B vitamins assist in homocysteine metabolism. Folic acid serves as a methyl donor and vitamin B-12 as a coenzyme in the conversion of homocysteine to methionine.
Biotin and pantothenic acid are also coenzymes essential for energy production from dietary fats, carbohydrates, and proteins. Pantothenic acid is a component of coenzyme A and of phosphopantetheine, and is therefore essential for Krebs cycle operation. Biotin is involved in many carboxylation reactions associated with gluconeogenesis, the Krebs cycle, and fatty acid synthesis.
While not truly vitamins choline, inositol, and para-aminobenzoic acid are important nutrients related to B vitamins. Choline serves as a methyl donor for homocysteine metabolism following conversion to betaine, as a structural component of cellular membranes as phosphatidylcholine, and as a neurotransmitter as acetylcholine. Inositol aids in the cellular response to hormonal signals, serves as a source of arachidonic acid, and is active in cellular membranes as phosphatidylinositol. Finally, para-aminobenzoic acid has antioxidant properties.