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Ortho Molecular
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Cardiovascular Health
Ubiquinol, one of the body's primary lipid-soluble antioxidants, boosts cellular energy production and provides a wide range of cardiovascular, cognitive, and metabolic health benefits.
CoQ10, or ubiquinone, is a lipid-soluble antioxidant that is found in every cell in the body. CoQ10 is abundant in the mitochondrial membrane and plays an important role in the synthesis of adenosine triphosphate (ATP), a molecule of chemical energy upon which all cellular functions depend. The synthesis of ATP within the mitochondria is a multi-step series of biochemical reactions called the electron transport chain. As a coenzyme, CoQ10 is required for several enzymatic reactions required to produce cellular energy and to protect the body against free radicals produced during this process. To maintain energy production, mitochondrial CoQ10 is continuously recycled from ubiquinone, its ATP production state, to ubiquinol, its antioxidant, free radical scavenging state. CoQ10, has been shown to extend cell life and benefit high-energy systems like the cardiovascular, neurological, and immune systems.
Key Benefits and Features:
| Serving Size: 1 Soft Gel Capsule | Amount/Serving |
| Ubiquinol (Kaneka Ubiquinol) | 100 mg |
Other Ingredients: D-Limonene Oil, Gelatin, Glycerin, Purified Water, Caprylic Acid, Capric Acid, Caramel Liquid, and Alpha Lipoic Acid.
Take 1 soft gel capsule per day, or as recommended by your health care professional.
Warning: If you are pregnant or nursing, consult with your health care practitioner before taking this product. Keep out of the reach of children.
Storage: Keep tightly closed in a cool, dry place.
CoQ10 Depletion
The body’s ability to produce and metabolize CoQ10 has been reported to decrease with age. CoQ10 deficiency may be caused by insufficient dietary intake of CoQ10, impairment in CoQ10 production, drug-induced CoQ10 depletion, gene mutations, and oxidative stress. HMG-CoA reductase is an enzyme required for the synthesis of cholesterol and CoQ10. Cholesterol-lowering medications inhibit this enzyme in order to reduce cholesterol synthesis, but may also deplete CoQ10 status simultaneously. In the event of CoQ10 depletion, supplementation can improve CoQ10 status and help maintain optimal levels in the body.
Antioxidant Protection
Oxidative stress is a condition that occurs when there is an imbalance of free radicals and antioxidants required to neutralize them, leading to oxidative damage. The extent of oxidative stress depends on the rate at which free radicals are generated, the level of antioxidant reserves, and the rate of repair of cellular and tissue damage that has occurred. This process has a significant impact on the body’s aging process. Ubiquinol is an electron donor because it has two hydroxyl groups. The electrons that ubiquinol donates help to neutralize free radicals, thereby providing significant protection against toxic oxidative reactions in the body.
Cholesterol
CoQ10 appears to be a preventive factor for reducing low-density lipoprotein (LDL) oxidation- a major factor for supporting healthy cholesterol levels. In a study examining the antioxidant effects of ubiquinol versus vitamin E, ubiquinol significantly reduced LDL lipid peroxidation more efficiently than vitamin E.
Cardiovascular Health
CoQ10 is important for all energy-dependent processes, including contraction of the heart muscle. CoQ10 is also important for the protection against free radical damage to the arterial vessels. In a double-blind, crossover trial, 19 patients received 100 mg/day or a placebo for 12 weeks. Compared with placebo, patients receiving CoQ10 demonstrated significant support of cardiac function and increased tolerance for physical activity. In another study, 109 patients received an average dose of 225 mg of CoQ10 per day. After a mean treatment period of over four months, CoQ10 helped maintain healthy blood pressure levels in more than half of the patients.
