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Enhanced B-Complex Support for Mitochondrial and Nerve Health
Ultra B-Complex w/PQQ combines essential B vitamins with PQQ to support mitochondrial bioenergetics and function. The B-complex vitamins, which are essential to basal mitochondrial function, serve as metabolic coenzymes and/or methyl donors. Thiamin and niacin support healthy neuron cell longevity, neuronal membrane function, and impulse conduction. L-5-MTHF, methylcobalamin and vitamin B6 support neuronal health as methylation cofactors in myelin and neurotransmitter biosynthesis.
Key Benefits and Features:Â
| Serving Size: 1 Vegetarian Capsule | Amount/Serving |
| Thiamin (as thiamin HCI)Â | 125 mg |
| Riboflavin (Vitamin B2 and 60% riboflavin 5' phosphate (activated B2)) | 12.7 mg |
| Niacin (as niacinamide and 8% inositol hexaniacinate (no-flush niacin)) | 108 mg |
| Vitamin B6 (as pyridoxine HCI and 7% pyridoxal 5' phosphate (activated B6)) | 96.7 mg |
| Folate (as Metafolin, L-5-MTHF) (400 mcg L-5-MTHF) | 667 mcg DFEÂ |
| Vitamin B12 (as methylcobalamin and 50% adenosylcobalamin)Â | 1,000 mcg |
| Biotin | 400 mcg |
| Pantothenic acid (as calcium pantothenate) (B5)Â | 100 mg |
| Alpha lipoic acid (thioctic acid)Â | 100 mg |
| Luteolin | 20 mg |
| BioPQQ pyrroloquinoline quinone disodium salt | 10 mg |
Other Ingredients: Vegetarian capsule (cellulose, water) and ascorbyl palmitate.
Does Not Contain: Wheat, soy, dairy, eggs, artificial colors, artificial sweeteners, coatings, shellacs, GMOs, tree nuts, peanuts, sesame, unnecessary binders, fillers, preservatives, magnesium stearate, gluten, trans fat, and hydrogenated oils.Â
Non-GMO, VegetarianÂ
As a dietary supplement, take 1 capsule, 1-2 times daily, with meals.Â
Warning: If you are pregnant or lactating, have any health condition, or are taking any medication, consult your health professional before use.Â
Storage: Store in a cool, dry place.Â
Adenosylcobalamin is the active form of vitamin B12 in mitochondria, where it maintains cellular energy (ATP) production by acting as a cofactor for MCM (methylmalonyl CoA mutase), whose activity declines with age in animal models. Animal studies suggest that adenosylcobalamin enhances mitochondrial bioenergetics, maintains type IIA fast-twitch muscle fiber size in aging animals, and maintains neuromuscular junction integrity. Preliminary data show that adenosylcobalamin also supports healthy myelination of peripheral neurons innervating muscle.
PQQ provides B vitamin-like activity with unique antioxidant properties. PQQ supports mitochondrial, neuronal, and cellular function, at least in part by activation of Nrf2 and antioxidant gene expression. PQQ may also help to maintain cytokine balance. Studies indicate significant support for cognitive function, including increased cerebral blood flow and oxygen metabolism.
Preliminary research suggests that PQQ promotes mitochondrial biogenesis by targeting SIRT1 and PGC-1α.4 Alpha lipoic acid provides additional support for mitochondrial energy utilization. Alpha lipoic acid and luteolin are both antioxidants that support neuronal health. Research suggests luteolin also helps maintain healthy macrophage activity and gene expression in the nervous system.
