Douglas Laboratories Ultra Preventive Vision
Ultra Preventive® Vision is a multivitamin/mineral formula specially designed to support ocular health with specific phytonutrients and carotenoids. Included in this formula is a lutein to zeaxanthin ratio of 3:1, which has been shown in research to contribute to a healthy macula and vision. Additionally, nutrients such as vitamin C, alpha-lipoic acid, green tea, and resveratrol provide antioxidant activity to the eyes. Activated forms of B-vitamins, such as methylated folate (5-MTHF), vitamin B12 (methylcobalamin), and thiamine (benfotiamine) are easily assimilated to support maxiumum clinical benefit.
Each serving contains:
Vitamin A (as retinyl palmitate) - 2,500 IU
Vitamin C (as ascorbic acid) - 500 mg
Vitamin D3 (as cholecalciferol) - 1,000 IU
Vitamin E (as d-alpha tocopheryl succinate) - 200 IU
Thiamine (as thiamine HCl) - 5 mg
Riboflavin - 10 mg
Niacinamide - 50 mg
Vitamin B6 - 10 mg
(as Pyridoxine HCl/Pyridoxal-5-Phosphate complex)
Folate (as L-methylfolate, Metafolin®) - 400 mcg
Vitamin B12 (as methylcobalamin) - 100 mcg
Biotin - 400 mcg
Folate (as L-methylfolate, Metafolin®) - 300 mcg
Pantothenic Acid (as calcium pantothenate) - 10 mg
Iodine (from kelp) - 150 mcg
Magnesium (as magnesium citrate) - 100 mg
Zinc (as zinc monomethionine) - 20 mg
Selenium (as amino acid chelate) - 100 mcg
Chromium (as amino acid chelate) - 120 mcg
Molybdenum (as amino acid chelate) - 75 mcg
Potassium (as Potassium aspartate) - 30 mg
L-Taurine - 150 mg
N-Acetyl L-Cysteine - 100 mg
Alpha-lipoic acid - 50 mg
Green tea leaf extract - 50 mg
( Camellia sinensis , standardized to 98% polyphenols and 45% EGCG, decaffeinated)
Grape Seed Extract ( Vitis vinifera ) - 25 mg
(standardized to 95% polyphenols)
Bilberry fruit Extract ( Vaccinium myrtilius ) - 15 mg
Lutein (from Marigold flower) - 12 mg
Resveratrol (as trans-resveratrol) - 10 mg
Benfotiamine - 5 mg
Zeaxanthin - 4 mg
Other ingredients: Hydroxypropyl methylcellulose (capsule), cellulose, vegetable stearate, silica.
As a dietary supplement, adults take 4 capsules daily in divided doses with meals or as directed by your healthcare professional.
More than any other tissue in the body, the ocular lens and retina are continually exposed to free radical damage and intense light radiation. Both light and oxygen can create free radicals that disturb membrane lipids of visual cells. Experts believe that the uncontrolled generation of free radicals in the eyes can ultimately lead to degeneration of the macula with vision loss or cataracts. Therefore, ocular tissue relies on a strong antioxidant defense system to protect them from free radical damage. Ultra Preventive Vision supplies powerful antioxidants in addition to essential basic vitamins and minerals for overall healthy aging.
Extracts of bilberry, grape seed, resveratrol, and green tea are rich sources of flavonoids that provide potent antioxidant defense in retinal visual cells and help maintain healthy vascularization in ocular tissue. Glutathione and selenium are essential components for healthy activity of the antioxidant enzyme glutathione peroxidase which is abundant in healthy eyes. Glutathione peroxidase levels, however, decline with advancing age, and an adequate dietary supply of glutathione, its precursor N-acetyl-L-cysteine, and selenium may help maintain healthy levels of this important enzyme. Carotenoids in Ultra Preventive Vision, such as lutein and zeaxanthin, are also important antioxidants in the macula of the eye as evidenced by recent studies performed by the NIH National Eye Institute. Research has shown that these important carotenoids are the predominant pigments found in the macula and occur naturally in serum at a ratio of 3:1 lutein to zeaxanthin.
Vitamin A functions in the retinal cells as a component of rhodopsin, a light-sensitive pigment that supports night vision. Cofactor minerals zinc and magnesium are found in high concentrations in the ocular tissue. Zinc is not only essential for normal visual signal transduction in the retina, but also is a cofactor for many of the enzymes involved in vitamin A dependent photo-transduction in the rod cells. Moreover, zinc is an essential cofactor of superoxide dismutase (SOD), an antioxidant enzyme that removes potentially dangerous superoxide radicals in the visual cells, the lens, and other tissues. Taurine, the most abundant free amino acid in ocular tissue, is thought to help stabilize neural membranes in retinal cells and modulate photoreceptor activity. A recent study showed a significant improvement in visual function after vitamin D supplementation, suggesting that vitamin D-3 supports the retina and age-related vision.
Ultra Preventive Vision contains methylated B vitamins for increased bioavailability to the body, including benfotiamine, a fat-soluble form of thiamine. Metafolin®, a patented, natural form of (6S) 5- methyltetrahydrofolate (5-MTHF) is the naturally occurring, predominant form of folate commonly found in cells and is essential for retinal health and methylation support. Unlike synthetic folic acid, L-methylfolate can be used directly by the body, without the need for an additional conversion via the enzyme (5,10 methylenetetrahydrofolate reductase (MTHFR)). In certain populations, the body’s ability to convert folic acid to 5-MTHF by use of this enzyme may be compromised due to genetic differences. Metafolin® contains only the S isomer of 5-MTHF and has been shown to be the only form of folate to be able to cross the blood-brain barrier.