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Calcium D-Glucarate - 90 Capsules Default Category Klaire Labs
Calcium D-Glucarate - 90 Capsules Default Category Klaire Labs
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    Calcium D-Glucarate - 90 Capsules



    Klaire Labs Calcium D-Glucarate has been discontinued by the manufacturer. 

    Supports Healthy Estrogen Metabolism

    An important source of D-Glucarate that supports your body's detoxification processes which removes toxins and steroid hormones like estrogen from your body.

    D-glucarate plays a vital protective role for the immune system by inhibiting the beta-glucuronidase enzyme that can otherwise interfere with the safe removal of steroid hormones such as estrogen.


    Serving Size: 1 Capsule
    Calcium (as calcium D-glucarate)
    80 mg
    Calcium-D-Glucarate‡ 500 mg

    Other Ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), microcrystalline cellulose, and silicon dioxide.

    Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and yeast. Contains no artificial colors, flavors, or preservatives.

    ‡CDGlucarate™ brand.

    Suggested Use

    1 capsule, 1 to 3 times daily with food or as directed by a healthcare professional.

    Caution: If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your physician before using this product. KEEP OUT OF REACH OF CHILDREN.

    More Info.

    What is Calcium D-Glucarate?

    Calcium D-Glucarate is a patented form of D-glucarate (also known as D-glucaric acid), a naturally occurring substance in the body that is involved in the metabolism and disposal of toxins and excess hormones, such as estrogen. In the diet, D-glucarate is found primarily in fruits and vegetables such as apples, grapefruit, oranges, bean sprouts, and broccoli. It is also produced in small amounts in the body.

    What does Calcium D-Glucarate do?

    Studies show that Calcium D-Glucarate supplementation supports healthy immune function, promotes estrogen metabolism, and enhances the body’s detoxification systems through inhibition of beta-glucuronidase, an enzyme that can interfere with normal hormone metabolism.

    How does Calcium D-Glucarate work?

    Upon ingestion, D-glucarate is slowly released from Calcium D-Glucarate and forms a compound that inhibits the enzyme beta-glucuronidase. This enzyme reduces the excretion of toxins and steroid hormones, including estrogen. Although beta-glucuronidase has some useful functions in the body, it can become overactive as a result of shifts in the gut microbiome, allowing toxins and hormones to be reabsorbed back into the body instead of being excreted. The slow-release nature of Calcium D-Glucarate inhibits about 50% of the enzyme activity over a five-hour period, thus helping the body to safely remove undesirable amounts of estrogen and other compounds. Because beta-glucuronidase enzymes are present in the liver, kidney, spleen, intestines, reproductive organs, and many other tissues, the beneficial actions of Calcium D-Glucarate may occur throughout the body.

    Who should take Calcium D-Glucarate?

    Anyone concerned about assisting the body’s natural detoxifying ability can take Calcium D-Glucarate as it is a very safe, well-tolerated compound. It is especially suitable for individuals with routine exposure to environmental agents who wish to ensure an added measure of protection beyond that provided by antioxidants. Calcium D-Glucarate may be especially important for women concerned about maintaining healthy breast tissue.