Poor Joint Health: America's leading cause of adult disability. New Study Confirms: natural combination of glucosamine and chondroitin sulfate proven best for joint health.h2. Glucosamine SulfateGlucosamine Sulfate is a chondroprotective agent that is a major building block of both cartilage and joint fluid. Numerous clinical trials have proven the effectiveness of glucosamine.h2. Chondroitin SulfateOral doses are shown to reach the joint and bolster the function of cartilage, and as such, act as a natural shock absorber for the joint. Without a good supply of chondroitin sulfate and fluid, some tissues may become malnourished, drier, thinner and more fragile. Use of non-steroidal anti-inflammatory drugs (ibuprofin, aspirin) blocks formation of connective tissue. Studies have shown that absorption of chondroitin sulfate is dependent upon the size of the molecule. The chondroitin sulfate found in Chondro-Flx is derived from a natural enzyme process, resulting in a small molecule size that enhances the valuable absorption necessary for product efficacy. The addition of the natural tissue support agent, bromelain, enhances the absorption of chondroitin sulfate.h2. Formula SynergyIn vitro, animal and human studies all confirm that glucosamine combined with chondroitin has synergistic benefits on cartilage tissues and is superior to single nutrients and other common options.