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Combines Protective Benefits of Indole-3-Carbinol and Diindolylmethane
Dietary indole compounds as found in broccoli, cabbage, and other cruciferous vegetables exert a strong protective effect on tissues such as the breast, cervix, and prostate that are most susceptible to the effects of undesirable estrogen metabolites, such as 16-alpha-hydroxyestrone. Indole compounds favorably influence steroid hormone metabolism and help rebalance estrogen in favor of 2-hydroxyestrone, a protective estrogen metabolite. Dietary indoles also stimulate liver detoxification enzymes, protect DNA, and regulate cell cycle progression. Indole-3-carbinol (I3C), the most prominent dietary indole, readily breaks down in the presence of stomach acid into diindolylmethane (DIM) and other associated indole compounds that are subsequently absorbed. Indole Forté™ contains I3C, DIM, and other indoles for broad protection.
Indole compounds like those in cruciferous vegetables help protect tissues such as the breast, cervix, and prostate against the effects of undesirable estrogen metabolites.
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Serving Size: 1 Capsule |
Amount/Serving |
| Total Dietary Indoles Proprietary blend containing indole-3-carbinol and diindolylmethane |
400 mg |
Other Ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), microcrystalline cellulose, ascorbyl palmitate, and silicon dioxide.
Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
Indole Forté™ contains a mixture of two important dietary indoles, indole-3-carbinol (I3C) and diindolylmethane (DIM). Since I3C undergoes biochemical transformation to related indole metabolites, broad-spectrum indoles may be present upon absorption.
1 capsule, 1 to 2 times daily or as directed by a healthcare professional.
Caution: If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your physician before using this product. KEEP OUT OF REACH OF CHILDREN.
Why is estrogen balance and metabolism important?
Maintaining estrogen balance and efficient estrogen metabolism is essential to preserving healthy tissues such as those of the breast, cervix, and prostate. Xenobiotics (substances foreign to the body) such as pesticides, poor diet, and genetic factors can shift the ratio and presence of estrogen metabolites in the body, encouraging dominance of less desirable estrogen metabolites, such as 16-alpha-hydroxyestrone. Research suggests that dietary indoles, as found in broccoli, cabbage, cauliflower, and other cruciferous vegetables, may exert a protective effect on tissues of the breast, cervix, and prostate by supporting the shifting the balance of estrogens to the more favorable metabolites.
How do indole compounds protect estrogen-sensitive tissues?
Research suggests that dietary indoles, as found in broccoli, cabbage, cauliflower, and other cruciferous vegetables, may support estrogen-responsive tissues of the breast, cervix, and prostate by encouraging a shift from less desirable estrogen metabolites (such as 16-alpha-hydroxyestrone) to the more favorable and protective ones like 2-hydroxyestrone.
What is the difference between I3C, DIM, and other indoles?
I3C is a major dietary indole compound in cruciferous vegetables with important cell- and estrogen metabolism-supporting actions. Diindolylmethane (DIM) is a breakdown product of I3C. Research suggests that DIM may be responsible for many of the beneficial actions attributed to I3C. Unlike some indole supplements that contain only I3C or DIM, Indole Forté™ contains a spectrum of indole compounds to support estrogen balance, detoxification enzymes of the liver, and exert other cell-protective benefits in both men and women.. Each capsule supplies 400 mg of total dietary indoles.
