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Methyl Balance™ - 60 Capsules Default Category Klaire Labs
Methyl Balance™ - 60 Capsules Default Category Klaire Labs

    Methyl Balance™ - 60 Capsules



    Klaire Labs Methyl Balance™ 

    Activated B Vitamins Plus TMG

    Methyl Balance™ is a unique formula that combines bioactive forms of four essential B vitamins with trimethylglycine (betaine). Vitamins B2, B6, B12, and folate are provided in active, coenzyme forms for maximal bioavailability and function. The ingredients in Methyl Balance™ work together to synergistically support methylation processes and help maintain normal homocysteine metabolism.

    Product Features:

    • The ingredients in Methyl Balance™ support healthy methylation in a variety of body systems, including liver detoxication, cardiovascular, neurological, and metabolic health by supporting SAMe production and the formation of methyl groups.
    • Active forms of vitamins B2 and B6 are provided for improved absorption and bioavailability.
    • Biologically active folate (as methylfolate, Metafolin®) and vitamin B12 (methylcobalamin) are included in the formula.


    Serving Size: 1 Vegetarian Capsule 
    Riboflavin (as riboflavin 5’-phosphate) 30 mg
    Vitamin B6 (as pyridoxal 5’- phosphate) 15 mg
    Folate (as Metafolin®‡ calcium L-5- methyltetrahydrofolate) 1,360 mcg DFE (800 mcg)
    Vitamin B12 (as methylcobalamin) 1,000 mcg 
    Betaine (trimethylglycine) 600 mg

    Other Ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), ascorbyl palmitate, microcrystalline cellulose, and silicon dioxide.

    Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and corn. Contains no artificial colors or flavors.

    ‡Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany.

    Suggested Use

    1 capsule daily with food or as directed by a healthcare professional.

    Caution: If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your physician before using this product. KEEP OUT OF REACH OF CHILDREN.

    More Info.

    Methylation is a biochemical reaction involving the transfer of a one-carbon methyl group from one molecule to another. This deceptively simple molecular modification is critically important and enables living organisms to alter protein functions and cellular activities in response to changes in both internal and external environmental conditions. For example, in neural tissue, methylation of phospholipids helps regulate cell membrane fluidity and mediate cognition and neuronal synchronization. In pancreatic islet cells, methylation supports glucose-stimulated insulin secretion. Methylation of DNA is an important means of regulating gene expression and nuclear chromatin organization.

    Methylation activity is directly influenced by key nutrients such as B vitamins, betaine, and SAMe. One approach to optimizing methylation capacity in the body is to increase intake of nutritional cofactors that support production of SAMe and reduce the buildup of metabolites that may obstruct cellular methylation pathways. The most important nutrients to support healthy methylation are the active, coenzyme forms of vitamins B2, B6, B12, folate, and betaine.

    Metabolizing homocysteine is also an important step in maintaining healthy cardiovascular and cognitive function. Vitamin B6, B12, and folate work together to metabolize homocysteine to methionine. Betaine further supports the metabolism of homocysteine to methionine through an alternate pathway.