N-Acetyl-Glucosamine (NAG) is a simple amino sugar, a monosaccharide with an amino group as part of its structure. NAG is a nutrient, an intermediary metabolite, and a component of the glycocalyx coat carried by all the body’s cells. The glycocalyx is a layer of carbohydrate and proteins complexed together, sometimes also with lipid components, and anchored in the outer cell membrane. As a major contributor to the glycocalyx, NAG is involved in cell-to-cell attachment, contributes to the cell surface antigen patterns, and augments receptor functions.* Although located on the cell’s exterior surface, NAG is important for cell function.
|Serving Size: 1 Capsule
|Amount Per Serving
Other Ingredients: Hydroxypropyl methylcellulose, microcrystalline cellulose, L-leucine
As a dietary supplement, 1 capsule three times daily, or as directed by a healthcare practitioner.
In addition to sugar-coating our cells, NAG is also a building block for large molecular complexes, the extracellular cements that add bulk and strength to the connective tissues.* NAG is a metabolic jumping-off point for a complex, enzyme-regulated polymerization process that generates glycosaminoglycans (GAG), which in turn become further organized into cartilage, bone, ligaments, tendons, sclera, and other specialized connective tissues.
NAG is important for intestinal function.* It is prominent both in the glycocalyx of the absorptive cells of the intestinal mucosa and in the mucus that is secreted from other cells of the mucosa. NAG is a major constituent of the mucosal barrier layer that protects the living epithelium from digestive enzymes and other potentially damaging intestinal contents.