PureGG 25B - 60 Capsules

Description

Pure Encapsulations PureGG 25B  

Shelf-Stable; Highly Researched Probiotic to Support Immune, G.I., and Overall Health

PureGG 25B provides 25 billion CFU of Lactobacillus rhamnosus GG (LGG), one of the most extensively studied, clinically documented, and widely utilized probiotic strains. The efficacy and uses of LGG have been recognized in hundreds of clinical trials across all age groups, including children and pregnant women. It is well known for its favorable effects on bowel function, particularly abdominal comfort, bowel motility, and occasional diarrhea.

Key Benefits and Features: 

• Ages 18 and up
• Supports healthy gut microflora
• Promotes bowel function 
• Supports healthy immune balance
• Highly researched Lactobacillus rhamnosus GG to support immune, G.I., and overall health across all ages
• Human origin strain, selected for its resistance to gastric acidity, adhesion properties, and ability to support healthy gut microflora
• Provides 25 billion CFU per capsule, one of the most characterized and clinically studied probiotic strains on the market
• Soy-free, dairy-free formulation
• Shelf-stable
• Made with high-quality vegetarian ingredients backed by verifiable science

For more information, check out our blog post - Brand Introduction: Pure Encapsulations.

Ingredients

Other Ingredients: Vegetarian capsule (cellulose, water).

Does Not Contain: Wheat, soy, dairy, eggs, artificial colors, artificial sweeteners, coatings, shellacs, GMOs, tree nuts, peanuts, sesame, unnecessary binders, fillers, preservatives, magnesium stearate, gluten, trans fat, and hydrogenated oils. 

Dairy Free, Gluten Free, Non-GMO, Soy Free, Vegetarian

Suggested Use 

Take 1 capsule daily, with or between meals.

Warning: Probiotics may be contraindicated for immunocompromised individuals. If you are pregnant or lactating, have any health condition or are immunocompromised, or are taking any medication, consult your health professional before use.

Storage: Store in a cool, dry place.

More Info. 

LGG was first isolated in 1983 from a human donor by Dr. Sherwood Gorbach and Dr. Barry Goldin (the "GG" namesake)  and patented in 1985. It has been in clinical use since 1990.  Originally selected for its resilience and colonization properties in the GI tract, LGG exhibits well-characterized resilience in the GI tract, with robust acid and bile tolerance. Pili on the cell surface of LGG express unique proteins that enable adhesion and adequate contact with intestinal epithelial cells. These interactions facilitate beneficial effects on mucosal integrity, immunity, and motility.

WHO IS THIS SUPPLEMENT FOR?

• Patients with occasional abdominal discomfort and/or diarrhea
• Patients seeking immune support

MECHANISMS OF ACTION

LGG promotes cytokine balance in the GI tract at the level of gene expression and provides general immunomodulatory support. In preclinical models, LGG also supports intestinal barrier integrity and mucin production.

CLINICAL RESEARCH HIGHLIGHTS

Occasional diarrhea and abdominal comfort

• In a study involving 820 people traveling on holiday to southern Turkey, LGG supplementation resulted in significant support for occasional diarrhea, particularly for older individuals, compared to placebo
• In a study involving 141 children with abdominal discomfort, supplementation for 12 weeks offered significant support for abdominal comfort and intestinal integrity.

Immunomodulation in the GI tract

• In a clinical trial, LGG supplementation promoted healthy gene expression to support white blood cell (WBC) function. Elderly subjects who received LGG for 28 days showed 95 differentially expressed genes related to cellular movement, cell-to-cell signaling, and cytokine response.
• In a double-blind, crossover study, supplementation moderated the neutrophil and monocyte immune response in dairy-challenged milk-sensitive subjects, while promoting immune function in non-sensitive subjects.

Gut microbiota

• In a clinical study, infants whose mothers had received LGG during the last weeks of pregnancy showed increased bifidobacterial diversity at 5 days of age.

Respiratory and immune health 

• In a study involving children ages 1-7 attending day care, supplementation showed statistically significant support for upper respiratory tract health and immune function.