ZenMind® Nighttime includes the same amount of GABA and L-Theanine as the best-selling original formula ZenMind®, augmented with vitamin B6 as P5P, and 5-HTP, the precursor to serotonin and melatonin. The combination helps promote a relaxed state, and provides the necessary factors for the body to produce melatonin, supporting normal, healthy sleep.
|Serving Size 2 veggie capsules||Amount Per Serving|
|GABA (gamma aminobutyric acid)||550 mg|
|Vitamin B6 (as Pyridoxal-5-Phosphate)||10 mg|
Other Ingredients: Hydroxypropyl methylcellulose, Microcrystalline cellulose, L-leucine
As a dietary supplement, 2 capsules 30 minutes before bedtime, or as directed by a healthcare practitioner.
Warnings: Not indicated for pregnant or nursing women. If taking antidepressants or other psychotropic medications, use only under the supervision of a qualified healthcare practitioner.
5-hydroxytryptophan (5-HTP) is obtained from the seeds of the African shrub Griffonia simplicifolia. In the body, 5-HTP has a variety of ways it may support healthy brain function. 5-HTP is converted in the body to serotonin, which can affect sleep, appetite, temperature, sexual behavior, pain sensation, and mental states. Serotonin is further converted into melatonin, the well-known sleep hormone. Vitamin B6 is required for amino acid, carbohydrate, and lipid metabolism. It is required for numerous metabolic transactions in the body, including the conversion of 5-HTP to serotonin. The typical form of B6 in supplements is pyridoxine, which requires further transformation to have its full effect. The coenzyme form of B6, pyridoxal-5-phosphate, is the active form of pyridoxine, and supports metabolic needs for a wider range of individuals. GABA is the major inhibitory neurotransmitter in the brain and is active at 20% of central nervous system synapses. GABA, via its neuronal A receptor, inhibits neurons by causing an influx of chloride ions. This chloride influx initiated by GABA is known to be part of the bodily mechanisms involved with mood, muscle relaxation and sedation. A decrease in GABA’s function as an inhibitory mediator or a dysregulated sensitivity of GABA receptors can lead to excessive neuronal activity. Theanine is also recognized to have calming properties. Theanine offers a unique combination of actions, allowing it to help relieve occasional sleeplessness, and at other times to help restore calm alertness when experiencing fatigue or drowsiness. Human studies have demonstrated that oral theanine supplementation increases alpha wave activity, fostering a state of calm relaxation. Theanine also supports a normal, healthy attitude during premenstrual syndrome (PMS). It may diminish the normal symptoms of PMS, and help reduce mood symptoms such as crying and irritability associated with PMS. Although L-theanine is a component of green tea, ZenMind® Nighttime does not contain caffeine. We use only Suntheanine®, pure L-theanine from Taiyo International, Inc.