MegaSporeBiotic™ is one of the most recognized names in the probiotic industry. It is Microbiome Labs’ flagship probiotic product—a pioneering and trend-setting all-spore formula designed to support gut microbiome reconditioning. MegaSporeBiotic™ is a 100% spore-based, broad-spectrum probiotic clinically tested to support and maintain gut microbial diversity, healthy levels of commensal gut bacterial species, and intestinal barrier function. This unique blend of spore-based probiotic species is designed to maintain survivability, efficacy, and potency throughout the digestive process. Boasting a 3-year shelf-life, MegaSporeBiotic™ doesn’t require refrigeration or a high colony-forming unit (CFU) count to be effective—unlike non-spore-forming strains (Bifidobacterium or Lactobacillus spp.), which are typically vulnerable to destruction at room temperature and in the digestive tract.
You can also purchase this trio as a kit: Total Gut Restoration Kit
For more information, check out our blog posts - Microbiome Labs: The Future of the Gut Health Industry, What I Wish I Knew About These Soil-Based Probiotics, & Top 5 Formulas for Digestion and GI Wellness
Serving Size: 2 Capsules
Proprietary Probiotic Blend
Bacillus indicus, HU36
Bacillus subtilis, HU58
Bacillus coagulans (SC-208)
Bacillus licheniformis (SL-307)
Bacillus clausii (SC-109)
4 Billion CFU
Other Ingredients: Cellulose, vegetable capsule (cellulose and water).
Adults and children over 5 years of age: Start with 1/2 or 1 capsule with a meal and slowly increase using the following protocol:
|Week 1||Take 1 capsule every other day|
|Week 2||Take 1 capsule daily|
|Week 3+||Take 2 capsules daily|
Children under 5 years of age, please consult with your healthcare practitioner.
Note: If 1 capsule every other day causes side effects, try starting with 1/2 capsules or even 1/4 capsule in some cases. Possible side effects may include abdominal cramping, loose stools, and changes in bowel movements. Though these side effects may be uncomfortable, they are a sign that the product is working! Side effects should resolve within 2-3 days.
Caution: If you are pregnant or nursing; taking any medication; have a medical condition, consult your doctor before using this product. Keep out of reach of children Do not use if safety seal is broken or missing.
No refrigeration required.
The gut microbiome is a dynamic ecosystem easily disrupted by environmental and lifestyle factors. When it is imbalanced—in a state of "dysbiosis"—localized digestive discomforts, gut health challenges, and body-wide issues may occur. An imbalanced microbial environment can negatively impact clients’ daily lives. Microbiome Labs designed MegaSporeBiotic™ to support reconditioning an imbalanced microbial gut environment.
MegaSporeBiotic™ contains five Bacillus spore-forming bacterial strains. Spore-formers surround themselves with a protective coat, so they are naturally designed to navigate digestion with 99.99% survivability. They arrive in the gut, transition from spore to active form, and provide practical reconditioning support. MegaSporeBiotic™ can support increased microbial diversity, maintain healthy gut barrier and immune function, and support keystone bacterial species that produce valuable short-chain fatty acid (SCFAs) metabolites, including butyrate. SCFAs support many diverse physiological functions necessary for optimal health and well-being.
MegaSporeBiotic™ is the first, truly innovative, multi-spore-based probiotic. Supported by extensive clinical validation and developed to fill a massive therapeutic practice gap, MegaSporeBiotic™ is backed by over 9 published studies, with multiple, ongoing studies.